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- Table of Contents
Facts about Ran-binding protein 3.
In the absence of Ran-bound GTP prevents binding of XPO1/CRM1 into the nuclear pore complex. Binds to CHC1/RCC1 and raises the guanine nucleotide exchange activity of CHC1/RCC1.
Human | |
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Gene Name: | RANBP3 |
Uniprot: | Q9H6Z4 |
Entrez: | 8498 |
Belongs to: |
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No superfamily |
DKFZp586I1520; RAN binding protein 3; ran-binding protein 3; RAN-binding protein-3; RanBP3
Mass (kDA):
60.21 kDA
Human | |
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Location: | 19p13.3 |
Sequence: | 19; NC_000019.10 (5916139..5978140, complement) |
Widely expressed with high levels in testis and heart.
Cytoplasm. Nucleus.
PMID: 9637251 by Mueller L., et al. Human RanBP3, a group of nuclear RanGTP binding proteins.
PMID: 11571268 by Englmeier L., et al. RanBP3 influences interactions between CRM1 and its nuclear protein export substrates.