Ran-binding protein 3 (RANBP3)

Acts as a cofactor for XPO1/CRM1-mediated nuclear export, perhaps as export complex scaffolding protein. Bound to XPO1/CRM1, stabilizes the XPO1/CRM1-cargo interaction.

In the absence of Ran-bound GTP prevents binding of XPO1/CRM1 into the nuclear pore complex. Binds to CHC1/RCC1 and raises the guanine nucleotide exchange activity of CHC1/RCC1.