Ran-binding protein 10 Antibodies

AND RANBP10 ELISA kits, Ran-binding protein 10 Proteins

Many biological assays use antibodies to detect Ran-binding protein 10, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Ran-binding protein 10 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Ran-binding protein 10 antibodies...

We validate the specificity of these antibodies to Ran-binding protein 10 by testing them on tissues known to express RANBP10 positively and negatively. Browse below to find the RANBP10 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RANBP10 Infographic by Boster Bio

All RANBP10 Products

Product

Figures

Specificity

Applications

Price

Anti-Ran-binding protein 10 RANBP10 Antibody

Human

ELISA, IF, IHC-P, WB

$449
Cat # A09936
0.1 mg

RANBP10 (NM_020850) Human Recombinant Protein

$1249
Cat # PROTQ6VN20
20 µg

RANBP10 (NM_020850) Human Over-expression Lysate

Human

$628
Cat # LS057610
100 µg

RANBP10 Overview

Facts about Ran-binding protein 10.

RANBP10 3D structure. Source: alphafold

Ran-binding protein 10 (RANBP10)

Acts as a guanine nucleotide exchange factor (GEF) for RAN GTPase (By similarity). May play an essential role in hemostasis and in keeping microtubule dynamics with respect to both platelet form and function (By similarity).

May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. Improves dihydrotestosterone-induced transactivation activity of AR, in addition to dexamethasone-induced transactivation activity of NR3C1, but does not have an effect on estrogen- induced transactivation.

Gene Information

Human
Gene Name:	RANBP10
Uniprot:	Q6VN20
Entrez:	57610

Family

Belongs to:

RANBP9/10 family

Alternative Names

KIAA1464FLJ31165; RAN binding protein 10; ran-binding protein 10; RanBP10

Molecular Weight

Mass (kDA):
67.257 kDA

Genomic Context


Human

Location:	16q22.1
Sequence:	16; NC_000016.10 (67723068..67806560, complement)

Tissue Specificity

Broadly expressed, with highest levels in skeletal muscle.

Subcellular Localizations

Cytoplasm, cytosol. Nucleus. Predominantly cytoplasmic.

Diseases

Cell Transformation, Neoplastic
Hemorrhage
Autoimmunity
Infective Disorder
Malignant Neoplasm Of Prostate
Congenital Abnormality
Thrombus
Endometrial Polyp
Tissue Adhesions
Virus Diseases
Arterial Thrombosis

Malignant Neoplasms
Thrombosis
Lupus Erythematosus, Systemic
Janiceps
Immune System Diseases
Von Willebrand Disease

Pathways

Mitosis
Interphase
Transport
Nucleocytoplasmic Transport
Hemostasis
Rna Interference
Regulation Of Nucleocytoplasmic Transport
Cellular Process
Localization
Cytokinesis
Translation

Cell Cycle
Cell Growth
Pathogenesis
Microtubule Polymerization
Spindle Assembly
Secretion

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RANBP10

References

PMID: 14684163 by Wang D., et al. A novel MET-interacting protein shares high sequence similarity with RanBPM, but fails to stimulate MET-induced Ras/Erk signaling.

PMID: 18222118 by Harada N., et al. RanBP10 acts as a novel coactivator for the androgen receptor.