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- Table of Contents
Facts about UL-16 binding protein 5.
Human | |
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Gene Name: | RAET1G |
Uniprot: | Q6H3X3 |
Entrez: | 353091 |
Belongs to: |
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MHC class I family |
RAET1G; retinoic acid early transcript 1G protein; retinoic acid early transcript 1G pseudogene; retinoic acid early transcript 1G; ULBP5; ULBP-5
Mass (kDA):
37.106 kDA
Human | |
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Location: | 6q25.1 |
Sequence: | 6; NC_000006.12 (149916878..149923133, complement) |
Isoform 1 is highly expressed in colon and in a number of tumor cell lines and highly restricted in normal tissues. Both isoforms are frequently expressed in cell lines derived from epithelial cancers, and in primary breast cancers.
[Isoform 1]: Cell membrane; Lipid-anchor, GPI-anchor. Endoplasmic reticulum. Mainly found intracellularly.; [Isoform 2]: Secreted.
PMID: 15240696 by Bacon L., et al. Two human ULBP/RAET1 molecules with transmembrane regions are ligands for NKG2D.
PMID: 18544572 by Cao W., et al. Four novel ULBP splice variants are ligands for human NKG2D.