Paraspeckle component 1 Antibodies

AND PSPC1 ELISA kits, Paraspeckle component 1 Proteins

Many biological assays use antibodies to detect Paraspeckle component 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Paraspeckle component 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Paraspeckle component 1 antibodies...

We validate the specificity of these antibodies to Paraspeckle component 1 by testing them on tissues known to express PSPC1 positively and negatively. Browse below to find the PSPC1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PSPC1 Infographic by Boster Bio

All PSPC1 Products

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Product

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Specificity

Applications

Price

Anti-Paraspeckle component 1 PSPC1 Antibody

Human, Mouse, Rat

IP, IHC, WB

$405
Cat # A06348
100ul

PSPC1 (NM_001042414) Human Over-expression Lysate

Human

$960
Cat # LS055269
100 µg

Anti-PSPC1 Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A06348-1
100 µg/vial

PSPC1 Overview

Facts about Paraspeckle component 1.

PSPC1 3D structure. Source: alphafold

Paraspeckle component 1 (PSPC1)

Regulates, cooperatively with NONO and SFPQ, androgen receptor-mediated gene transcription activity in Sertoli cell line (By similarity). Binds to poly(A), poly(G) and poly(U) RNA homopolymers.

Regulates the circadian clock by repressing the transcriptional activator activity of this CLOCK-ARNTL/BMAL1 heterodimer (By similarity). Together with NONO, required for the formation of atomic paraspeckles.

Gene Information

Human
Gene Name:	PSPC1
Uniprot:	Q8WXF1
Entrez:	55269

Family

Belongs to:

PSPC family

Alternative Names

FLJ33554; paraspeckle component 1; paraspeckle protein 1; PSP1

Molecular Weight

Mass (kDA):
58.744 kDA

Genomic Context


Human

Location:	13q12.11
Sequence:	13; NC_000013.11 (19674752..19783036, complement)

Tissue Specificity

Expressed in pancreas, kidney, skeletal muscle, liver, lung, placenta, brain and heart.

Subcellular Localizations

Nucleus, nucleolus. Nucleus matrix. Cytoplasm. Nucleus speckle. In punctate subnuclear structures often located adjacent to splicing speckles, called paraspeckles. Colocalizes with NONO and SFPQ in paraspeckles and perinucleolar caps in an RNA-dependent manner. May cycle between paraspeckles and nucleolus. In telophase, when daughter nuclei form, localizes to perinucleolar caps.