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- Table of Contents
Facts about Platelet-derived growth factor C.
Required for normal skeleton formation during embryonic development, particularly for normal development of the craniofacial skeleton and for normal development of the palate. Required for normal skin morphogenesis during embryonic development.
Mouse | |
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Gene Name: | Pdgfc |
Uniprot: | Q8CI19 |
Entrez: | 54635 |
Belongs to: |
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PDGF/VEGF growth factor family |
FALLOTEIN; PDGFC; PDGF-C; platelet derived growth factor C; platelet-derived growth factor C; SCDGFSpinal cord-derived growth factor; secretory growth factor-like protein; VEGF-E
Mass (kDA):
38.741 kDA
Mouse | |
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Location: | 3|3 E3 |
Sequence: | 3; |
Mainly expressed in kidney, testis, liver, heart and brain (at protein level). Highly expressed in airway epithelium, interstitial cells and alveolar macrophages in the lung of mice overexpressing IL13. Expressed in the ovaries.
PMID: 10960785 by Ding H., et al. The mouse Pdgfc gene: dynamic expression in embryonic tissues during organogenesis.
PMID: 10806482 by Li X., et al. PDGF-C is a new protease-activated ligand for the PDGF alpha- receptor.