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- Table of Contents
Facts about PRA1 family protein 2.
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Human | |
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Gene Name: | PRAF2 |
Uniprot: | O60831 |
Entrez: | 11230 |
Belongs to: |
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PRA1 family |
PRA1 family protein 2
Mass (kDA):
19.258 kDA
Human | |
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Location: | Xp11.23 |
Sequence: | X; NC_000023.11 (49071161..49074002, complement) |
Strong expression in the brain, small intestine, lung, spleen, and pancreas as well as in tumor tissues of the breast, colon, lung and ovary, with a weaker expression in normal tissues of the same patient. High expression in neuroblastic tumors. Strongly expressed in Purkinje cells and more moderately in cells of the molecular and the granular layers in the cerebellum. Detected in neuronal cells, but not in non- neuronal cells in the cerebral cortex, hippocampus, and lateral ventricles.
Endosome membrane; Multi-pass membrane protein.
PMID: 15757671 by Schweneker M., et al. JM4 is a four-transmembrane protein binding to the CCR5 receptor.
PMID: 16481131 by Fo C.S., et al. Genomic organization, expression profile, and characterization of the new protein PRA1 domain family, member 2 (PRAF2).
*More publications can be found for each product on its corresponding product page