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- Table of Contents
Facts about Partitioning defective 6 homolog beta.
Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins.
Mouse | |
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Gene Name: | Pard6b |
Uniprot: | Q9JK83 |
Entrez: | 58220 |
Belongs to: |
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PAR6 family |
par-6 (partitioning defective 6, C.elegans) homolog beta; PAR-6 beta; par-6 partitioning defective 6 homolog beta (C. elegans); PAR6B; PAR-6B; partitioning defective 6 homolog beta
Mass (kDA):
41.067 kDA
Mouse | |
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Location: | 2|2 H3 |
Sequence: | 2; |
Expressed in pancreas and in both adult and fetal kidney. Weakly expressed in placenta and lung. Not expressed in other tissues.
PMID: 10934474 by Joberty G., et al. The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42.
PMID: 11839275 by Gao L., et al. Assembly of epithelial tight junctions is negatively regulated by Par6.