Pyrroline-5-carboxylate reductase 3 (PYCR3)

Enzyme that catalyzes the final step in proline biosynthesis. Proline is synthesized from either glutamate or ornithine; both are converted into pyrroline-5-carboxylate (P5C), and then to proline through pyrroline-5-carboxylate reductases (PYCRs).

PYCRL is exclusively linked to the conversion of ornithine to proline. .