PTPN13 Antibodies

AND PTPN13 ELISA kits, PTPN13 Proteins

Many biological assays use antibodies to detect PTPN13, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PTPN13 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PTPN13 antibodies...

We validate the specificity of these antibodies to PTPN13 by testing them on tissues known to express PTPN13 positively and negatively. Browse below to find the PTPN13 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PTPN13 Infographic by Boster Bio

All PTPN13 Products

Product

Figures

Specificity

Applications

Price

Anti-PTPN13/PTPL1 (FAP1) Antibody

5 Q&As

Human

IP, IHC, WB

$328
Cat # A02481
50 µl

PTPN13 (NM_006264) Human Over-expression Lysate

Human

$960
Cat # LS005783
100 µg

Anti-PTPN13 Antibody Picoband™

Human

ELISA, Flow Cytometry, WB

$370
Cat # A02481-1
100 µg/vial

PTPN13 Overview

Facts about Tyrosine-protein phosphatase non-receptor type 13.

PTPN13 3D structure. Source: alphafold

Tyrosine-protein phosphatase non-receptor type 13 (PTPN13)

Tyrosine phosphatase which regulates negatively FAS- induced apoptosis and NGFR-mediated pro-apoptotic signaling (PubMed:15611135). May regulate phosphoinositide 3-kinase (PI3K) signaling through dephosphorylation of PIK3R2 (PubMed:23604317).

Gene Information

Human
Gene Name:	PTPN13
Uniprot:	Q12923
Entrez:	5783

Family

Belongs to:

protein-tyrosine phosphatase family

Alternative Names

EAP-1; FAP-1; hPTPE1; PNP1; protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associatedphosphatase); protein-tyrosine phosphatase 1, Fas-associated; PTP1E; PTP1EDKFZp686J1497; PTP-BAS; PTP-BASEC 3.1.3.48; PTP-BL; PTP-E1; PTPL1; PTPL1nonreceptor type 13; PTPLE; PTPN13; tyrosine-protein phosphatase non-receptor type 13

Molecular Weight

Mass (kDA):
276.906 kDA

Genomic Context


Human

Location:	4q21.3
Sequence:	4; NC_000004.12 (86594307..86815176)

Tissue Specificity

Present in most tissues with the exception of the liver and skeletal muscle. Most abundant in lung, kidney and fetal brain.

Subcellular Localizations

Cytoplasm, cytoskeleton. Nucleus. Cell projection, lamellipodium. Colocalizes with F-actin (PubMed:10826496). Colocalizes with PKN2 in lamellipodia-like structure, regions of large actin turnover (PubMed:11356191).

Diseases

Malignant Neoplasms
Neoplasms
Carcinoma
Posttransfusion Purpura
Malignant Neoplasm Of Breast
Mammary Neoplasms
Adenocarcinoma
Malignant Tumor Of Colon
Cell Transformation, Neoplastic
Malignant Paraganglionic Neoplasm
Colonic Neoplasms
Leukemia
Malignant Neoplasm Of Ovary

Malignant Squamous Cell Neoplasm
Colorectal Cancer
Ovarian Neoplasm
Liver Carcinoma
Cell Invasion
Neoplasm Invasiveness
Colorectal Neoplasms

Interacting Proteins

FAS
PDCD10
RAPGEF6
SQSTM1

Pathways

Localization
Cell Death
Induction Of Apoptosis
Rna Interference
Cell Proliferation
Cytokinesis
Cell Cycle
Methylation
Cell Growth
Pathogenesis
Programmed Cell Death
Translation
Cell Migration

Spermatogenesis
Cell Division
Cell Motility
Cell Differentiation
Regulation Of Cytokinesis
Transport
Invasive Growth

PTMs

Phosphorylation
Dephosphorylation

Methylation
Cleavage

Biotinylation

Research Areas

Protein Phosphatase

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PTPN13

References

PMID: 8071359 by Banville D., et al. A novel protein-tyrosine phosphatase with homology to both the cytoskeletal proteins of the band 4.1 family and junction-associated guanylate kinases.

PMID: 8287977 by Maekawa K., et al. Molecular cloning of a novel protein-tyrosine phosphatase containing a membrane-binding domain and GLGF repeats.