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- Table of Contents
Facts about Polypyrimidine tract-binding protein 3.
Positive regulator of EPO-dependent erythropoiesis. Participates in cell differentiation regulation by repressing tissue-specific exons.
Human | |
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Gene Name: | PTBP3 |
Uniprot: | O95758 |
Entrez: | 9991 |
Belongs to: |
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No superfamily |
DKFZp781I1117; fission yeast differentiation regulator; PTBP3; regulator of differentiation (in S. pombe) 1; regulator of differentiation 1; ROD1 regulator of differentiation 1 (S. pombe); Rod1
Mass (kDA):
59.69 kDA
Human | |
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Location: | 9q32 |
Sequence: | 9; NC_000009.12 (112217715..112333669, complement) |
Expressed in several hematopoietic cell lines examined.
PMID: 10207106 by Yamamoto H., et al. Isolation of a mammalian homologue of a fission yeast differentiation regulator.
PMID: 18335065 by Robinson F., et al. Expression of human nPTB is limited by extreme suboptimal codon content.