Prostasin Antibodies

AND PRSS8 ELISA kits, Prostasin Proteins

Many biological assays use antibodies to detect Prostasin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Prostasin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Prostasin antibodies...

We validate the specificity of these antibodies to Prostasin by testing them on tissues known to express PRSS8 positively and negatively. Browse below to find the PRSS8 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: CBLIF Next: PSAP

PRSS8 Infographic by Boster Bio

All PRSS8 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Human Prostasin ELISA Kit PicoKine®

1 Citations 6 Q&As

Human

ELISA

$499
Cat # EK1272
96 wells/kit, with removable strips.

Mouse Prostasin ELISA Kit PicoKine®

5 Q&As

Mouse

ELISA

$499
Cat # EK1273
96 wells/kit, with removable strips.

Anti-Prostasin PRSS8 Antibody

Human, Mouse, Rat

$405
Cat # A05561
100ul

Anti-PRSS8 Antibody Picoband®

Human

ELISA, Flow Cytometry, WB

$370
Cat # A05561-2
100 µg/vial

PRSS8 Overview

Facts about Prostasin.

PRSS8 3D structure. Source: alphafold

Prostasin (PRSS8)

Possesses a trypsin-like cleavage specificity with a preference for poly-basic substrates. Stimulates epithelial sodium channel (ENaC) activity through activating cleavage of the gamma subunits (SCNN1G).

Gene Information

Human
Gene Name:	PRSS8
Uniprot:	Q16651
Entrez:	5652

Family

Belongs to:

peptidase S1 family

Alternative Names

CAP1; channel-activating protease 1; EC 3.4.21; EC 3.4.21.-; EC 3.4.21.120; Prostasin; protease, serine, 8; Prss8; Serine protease 8

Molecular Weight

Mass (kDA):
36.431 kDA

Genomic Context


Human

Location:	16p11.2
Sequence:	16; NC_000016.10 (31131433..31135727, complement)

Tissue Specificity

Found in prostate, liver, salivary gland, kidney, lung, pancreas, colon, bronchus and renal proximal tubular cells. In the prostate gland it may be synthesized in epithelial cells, secreted into the ducts, and excreted into the seminal fluid.

Subcellular Localizations

[Prostasin]: Cell membrane; Single-pass membrane protein.; [Prostasin light chain]: Secreted, extracellular space. Found in the seminal fluid. Secreted after cleavage of its C-terminus.; [Prostasin heavy chain]: Secreted, extracellular space. Found in the seminal fluid. Secreted after cleavage of its C-terminus.

Diseases

Neoplasms
Malignant Neoplasms
Dehydration
Carcinoma
Carcinoma, Transitional Cell
Kidney Neoplasm
Malignant Neoplasm Of Urinary Bladder
Carcinogenesis
Neoplasms, Glandular And Epithelial
Chromophobe Renal Cell Carcinoma
Skin Abnormalities
Oncocytic Neoplasm
Renal Cell Carcinoma

Malignant Neoplasm Of Ovary
Colorectal Cancer
Dysequilibrium Syndrome
Invasive Malignant Neoplasm
Bladder Neoplasm
Cell Invasion
Cell Transformation, Neoplastic

Pathways

Transport
Zymogen Activation
Localization
Methylation
Tube Closure
Neural Tube Closure
Translation
Dna Hypermethylation
Water Transport

Glycosylation
Skin Development
Demethylation

PTMs

Cleavage
Demethylation

Phosphorylation
Glycosylation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PRSS8

References

PMID: 7768952 by Yu J.X., et al. Molecular cloning, tissue-specific expression, and cellular localization of human prostasin mRNA.

PMID: 8034638 by Yu J.X., et al. Prostasin is a novel human serine proteinase from seminal fluid. Purification, tissue distribution, and localization in prostate gland.

1 Publications of Boster Prostasin Antibodies & ELISA Kits

PubMed ID: 10.3390/ijms22158314, Liver-Specific Overexpression of Prostasin Attenuates High-Fat Diet-Induced Meta...

*More publications can be found for each product on its corresponding product page