Prosaposin Antibodies

AND PSAP ELISA kits, Prosaposin Proteins

Many biological assays use antibodies to detect Prosaposin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Prosaposin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Prosaposin antibodies...

We validate the specificity of these antibodies to Prosaposin by testing them on tissues known to express PSAP positively and negatively. Browse below to find the PSAP antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PSAP Infographic by Boster Bio

All PSAP Products

Product

Figures

Specificity

Applications

Price

PSAP Prosaposin Human Recombinant Protein

Human

$250
Cat # PROTP07602
2ug, 10ug, 1mg

Anti-Saposin PSAP Antibody

Human

ELISA, IHC, WB

$380
Cat # A00937
100ul

Anti-PSAP Rabbit Monoclonal Antibody

Human

IHC, WB

$370
Cat # M00937
100 μl/vial

PSAP (NM_002778) Human Over-expression Lysate

Human

$628
Cat # LS005660
100 µg

Anti-PSAP Antibody Picoband™

Human

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A00937-1
100 µg/vial

PSAP Overview

Facts about Prosaposin.

PSAP 3D structure. Source: alphafold

Prosaposin (PSAP)

Saposin-A and saposin-C stimulate the hydrolysis of glucosylceramide by beta-glucosylceramidase (EC 3.2.

1.45) and galactosylceramide by beta-galactosylceramidase (EC 3.

Gene Information

Human
Gene Name:	PSAP
Uniprot:	P07602
Entrez:	5660

Family

Belongs to:

No superfamily

Alternative Names

FLJ00245; GLBA; proactivator polypeptide; prosaposin; PSAP; SAP1; SAP1MGC110993; sphingolipid activator protein-1

Molecular Weight

Mass (kDA):
58.113 kDA

Genomic Context


Human

Location:	10q22.1
Sequence:	10; NC_000010.11 (71816298..71851251, complement)

Subcellular Localizations

Lysosome.; [Prosaposin]: Secreted. Secreted as a fully glycosylated 70 kDa protein composed of complex glycans.

Diseases

Neoplasms
Prostatic Neoplasms
Malignant Neoplasm Of Prostate
Malignant Neoplasms
Carcinoma
Gaucher Disease
Adenocarcinoma
Leukodystrophy, Metachromatic
Leukodystrophy
Nervousness
Lysosomal Storage Diseases
Neoplasm Metastasis

Prostate Adenocarcinoma
Gangliosidoses
Sphingolipidoses
Storage Disease
Hyperplasia
Atrophy
Tay-sachs Disease

Interacting Proteins

CASP14
VCP
ZBED1

Pathways

Localization
Transport
Secretion
Cell Death
Glycosylation
Endocytosis
Translation
Pathogenesis
Cell Proliferation
Regeneration
Proteolysis
Lipid Storage

Cell Differentiation
Excretion
Cell Cycle
Fertilization
Brain Development
Light Absorption
Innervation

PTMs

Cleavage
Phosphorylation
Glycosylation
Biotinylation
Methylation

Deglycosylation
Reduction
Oxidation
Ubiquitination
Iodination

Research Areas

Cancer

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PSAP

References

PMID: 2515150 by Rorman E.G., et al. Molecular cloning of a human co-beta-glucosidase cDNA: evidence that four sphingolipid hydrolase activator proteins are encoded by single genes in humans and rats.

PMID: 2498298 by Nakano T., et al. Structure of full-length cDNA coding for sulfatide activator, a Co- beta-glucosidase and two other homologous proteins: two alternate forms of the sulfatide activator.