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- Table of Contents
Facts about Prominin-2.
Human | |
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Gene Name: | PROM2 |
Uniprot: | Q8N271 |
Entrez: | 150696 |
Belongs to: |
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prominin family |
hPROML2; MGC138714; PROM2; PROM-2; Prominin 2; prominin-2; Prominin-like protein 2; prominin-related protein; PROML2
Mass (kDA):
91.883 kDA
Human | |
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Location: | 2q11.1 |
Sequence: | 2; NC_000002.12 (95274449..95291320) |
Present in saliva within small membrane particles (at protein level). Expressed in kidney, prostate, trachea, esophagus, salivary gland, thyroid gland, mammary gland adrenal gland, placenta, stomach, spinal cord and liver. In submucosal tumor, expressed in spindle-shaped or stellate stromal cells. Expressed in prostate cancer cell lines.
Apical cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. Cell projection, microvillus membrane; Multi-pass membrane protein. Cell projection, cilium membrane; Multi-pass membrane protein. Colocalizes with PROM1. Associates with membrane in a cholesterol-dependent manner. Localizes to the apical and basolateral membranes of epithelial cells (By similarity).
PMID: 12514187 by Fargeas C.A., et al. Characterization of prominin-2, a new member of the prominin family of pentaspan membrane glycoproteins.
PMID: 12446606 by Zhang Q., et al. Identification and characterization of a novel testosterone-regulated prominin-like gene in the rat ventral prostate.