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PRKAR2B Antibodies
AND PRKAR2B ELISA kits, PRKAR2B Proteins
Many biological assays use antibodies to detect PRKAR2B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PRKAR2B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PRKAR2B antibodies...
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PRKAR2B Infographic by Boster Bio
All PRKAR2B Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M04943
100 μl
Cat # M04943
100 μl
Human, Mouse, Rat
ELISA
$480
Cat # EKC1462
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1462
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2269
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2269
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$405
Cat # A04943
100ul
Cat # A04943
100ul
Human, Monkey, Mouse, Rat
ELISA, IHC, WB
$380
Cat # A04943S113
100ul
Cat # A04943S113
100ul
PRKAR2B Overview
Facts about cAMP-dependent protein kinase type II-beta regulatory subunit.
cAMP-dependent protein kinase type II-beta regulatory subunit (PRKAR2B)
Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase.
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Gene Information
| Human | |
|---|---|
| Gene Name: | PRKAR2B |
| Uniprot: | P31323 |
| Entrez: | 5577 |
Family
| Belongs to: |
|---|
| cAMP-dependent kinase regulatory chain family |
Alternative Names
cAMP-dependent protein kinase type II-beta regulatory chain; cAMP-dependent protein kinase type II-beta regulatory subunit; H_RG363E19.2; PRKAR2; protein kinase, cAMP-dependent, regulatory, type II, beta; RII-BETA; WUGSC:H_RG363E19.2
Molecular Weight
Mass (kDA):
46.302 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 7q22.3 |
| Sequence: | 7; NC_000007.14 (107044705..107161811) |
Tissue Specificity
Four types of regulatory chains are found: I- alpha, I-beta, II-alpha, and II-beta. Their expression varies among tissues and is in some cases constitutive and in others inducible.
Subcellular Localizations
Cytoplasm. Cell membrane. Colocalizes with PJA2 in the cytoplasm and at the cell membrane.
Diseases
- Malignant Neoplasms
- Neoplasms
- Obesity
- Cell Transformation, Neoplastic
- Growth Arrest
- Neuroblastoma
- Dysequilibrium Syndrome
- Adenoma
- Malignant Tumor Of Colon
- Autoimmune Diseases
- Diabetes Mellitus
- Colonic Neoplasms
- Autoimmune Reaction
Interacting Proteins
- AKAP14
- PRKACA
Pathways
- Cell Growth
- Cell Proliferation
- Localization
- Cell Cycle
- Translation
- Sensitization
- Induction Of Apoptosis
- Regeneration
- Decidualization
- Secretion
- Muscle Cell Proliferation
- Cell Activation
- Response To Camp
PTMs
- Phosphorylation
Research Areas
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PRKAR2B
bosterbio.com/bosterbio-gene-info-cards/PRKAR2B
References
PMID: 2851102 by Levy F.O., et al. Molecular cloning, complementary deoxyribonucleic acid structure and predicted full-length amino acid sequence of the hormone-inducible regulatory subunit of 3'-5'-cyclic adenosine monophosphate-dependent protein kinase from human testis.
PMID: 21423175 by Lignitto L., et al. Control of PKA stability and signalling by the RING ligase praja2.