This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Facts about Peroxiredoxin-4.
Regulates the activation of NF-kappa-B in the cytosol by a modulation of I- kappa-B-alpha phosphorylation. .
Human | |
---|---|
Gene Name: | PRDX4 |
Uniprot: | Q13162 |
Entrez: | 10549 |
Belongs to: |
---|
peroxiredoxin family |
Antioxidant enzyme AOE372; AOE372; AOE37-2PRX-4; EC 1.11.1.15; Peroxiredoxin 4; Peroxiredoxin IV; peroxiredoxin-4; PRDX4; Prx4; prx-4; prx-IV; thioredoxin peroxidase (antioxidant enzyme); Thioredoxin peroxidase AO372; Thioredoxin-dependent peroxide reductase A0372
Mass (kDA):
30.54 kDA
Human | |
---|---|
Location: | Xp22.11 |
Sequence: | X; NC_000023.11 (23667493..23686397) |
Cytoplasm. Endoplasmic reticulum. Cotranslationally translocated to and retained within the endoplasmic reticulum. A small fraction of the protein is cytoplasmic.
PMID: 9388242 by Jin D.-Y., et al. Regulatory role for a novel human thioredoxin peroxidase in NF-kappaB activation.
PMID: 19892738 by Xu G., et al. Global profiling of protease cleavage sites by chemoselective labeling of protein N-termini.