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- Table of Contents
Facts about Putative histone-lysine N-methyltransferase PRDM6.
Plays a role in endothelial cells by inhibiting endothelial cell proliferation, survival and differentiation. It is unclear whether it's histone methyltransferase activity in vivo.
Human | |
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Gene Name: | PRDM6 |
Uniprot: | Q9NQX0 |
Entrez: | 93166 |
Belongs to: |
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class V-like SAM-binding methyltransferase superfamily |
PRDM6 PR domain containing 6; putative histone-lysine N-methyltransferase PRDM6
Mass (kDA):
64.452 kDA
Human | |
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Location: | 5q23.2 |
Sequence: | 5; NC_000005.10 (123089148..123194266) |
Nucleus.
PMID: 10668202 by Jiang G.L., et al. The yin-yang of PR-domain family genes in tumorigenesis.
PMID: 27181681 by Li N., et al. Mutations in the histone modifier PRDM6 are associated with isolated nonsyndromic patent ductus arteriosus.