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- Table of Contents
Facts about PR domain zinc finger protein 2.
Binds to the macrophage-specific TPA-responsive element (MTE) of this HMOX1 (heme oxygenase 1) gene and may function as a transcriptional activator of this gene. .
Human | |
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Gene Name: | PRDM2 |
Uniprot: | Q13029 |
Entrez: | 7799 |
Belongs to: |
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class V-like SAM-binding methyltransferase superfamily |
PR domain zinc finger protein 2
Mass (kDA):
188.915 kDA
Human | |
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Location: | 1p36.21 |
Sequence: | 1; NC_000001.11 (13698874..13825079) |
Highly expressed in retinoblastoma cell lines and in brain tumors. Also expressed in a number of other cell lines and in brain, heart, skeletal muscle, liver and spleen. Isoform 1 is expressed in testis at much higher level than isoform 3.
Nucleus.
PMID: 7538672 by Buyse I.M., et al. The retinoblastoma protein binds to RIZ, a zinc-finger protein that shares an epitope with the adenovirus E1A protein.
PMID: 9006946 by Liu L., et al. The retinoblastoma interacting zinc finger gene RIZ produces a PR domain-lacking product through an internal promoter.