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- Table of Contents
Facts about Axonemal dynein light intermediate polypeptide 1.
Human | |
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Gene Name: | DNALI1 |
Uniprot: | O14645 |
Entrez: | 7802 |
Belongs to: |
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inner dynein arm light chain family |
dJ423B22.5; dynein, axonemal, light intermediate chain 1; dynein, axonemal, light intermediate polypeptide 1; hp28axonemal dynein light intermediate polypeptide 1; Inner dynein arm light chain, axonemal; inner dynein arm, homolog of clamydomonas; P28dJ423B22.5 (axonemal dynein light chain (hp28))
Mass (kDA):
29.662 kDA
Human | |
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Location: | 1p34.3 |
Sequence: | 1; NC_000001.11 (37556940..37566857) |
Expressed in many tissues. A smaller 0.9 kb and a larger 2.5 kb transcripts were detected at the highest level in the testis, at medium levels in the prostate, heart, liver, lung and pancreas, at low levels in the ovary, skeletal muscle and small intestine. Not detected in spleen, colon epithelium, thymus or peripheral blood leukocytes. The 0.9 kb transcript is expressed at a 20-fold higher level than the 2.5 kb transcript in the testis.
Cell projection, cilium.
PMID: 9284741 by Kastury K., et al. Complementary deoxyribonucleic acid cloning and characterization of a putative human axonemal dynein light chain gene.
PMID: 27120127 by Jeanson L., et al. Mutations in GAS8, a gene encoding a nexin-dynein regulatory complex subunit, cause primary ciliary dyskinesia with axonemal disorganization.