DNALI1 Antibodies

AND DNALI1 ELISA kits, DNALI1 Proteins

Many biological assays use antibodies to detect DNALI1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DNALI1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DNALI1 antibodies...

We validate the specificity of these antibodies to DNALI1 by testing them on tissues known to express DNALI1 positively and negatively. Browse below to find the DNALI1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: CBLIF Next: PTP4A1

DNALI1 Infographic by Boster Bio

All DNALI1 Products

Product

Figures

Specificity

Applications

Price

DNALI1 (NM_003462) Human Recombinant Protein

$1249
Cat # PROTO14645
20 µg

DNALI1 (NM_003462) Human Over-expression Lysate

Human

$628
Cat # LS007802
100 µg

DNALI1 Overview

Facts about Axonemal dynein light intermediate polypeptide 1.

DNALI1 3D structure. Source: alphafold

Axonemal dynein light intermediate polypeptide 1 (DNALI1)

May play a dynamic role in flagellar motility. .

Gene Information

Human
Gene Name:	DNALI1
Uniprot:	O14645
Entrez:	7802

Family

Belongs to:

inner dynein arm light chain family

Alternative Names

dJ423B22.5; dynein, axonemal, light intermediate chain 1; dynein, axonemal, light intermediate polypeptide 1; hp28axonemal dynein light intermediate polypeptide 1; Inner dynein arm light chain, axonemal; inner dynein arm, homolog of clamydomonas; P28dJ423B22.5 (axonemal dynein light chain (hp28))

Molecular Weight

Mass (kDA):
29.662 kDA

Genomic Context


Human

Location:	1p34.3
Sequence:	1; NC_000001.11 (37556940..37566857)

Tissue Specificity

Expressed in many tissues. A smaller 0.9 kb and a larger 2.5 kb transcripts were detected at the highest level in the testis, at medium levels in the prostate, heart, liver, lung and pancreas, at low levels in the ovary, skeletal muscle and small intestine. Not detected in spleen, colon epithelium, thymus or peripheral blood leukocytes. The 0.9 kb transcript is expressed at a 20-fold higher level than the 2.5 kb transcript in the testis.

Subcellular Localizations

Cell projection, cilium.

Diseases

Frontotemporal Lobar Degeneration
Male Infertility
Malignant Neoplasm Of Breast
Neurodegenerative Disorders
Tumor Progression
Dementia
Malignant Paraganglionic Neoplasm
Infertility
Carcinoma

Motor Neuron Disease
Malignant Neoplasms
Neoplasms
Mammary Neoplasms

Interacting Proteins

HTT
PRMT6
SIAH1

PTMs

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DNALI1

References

PMID: 9284741 by Kastury K., et al. Complementary deoxyribonucleic acid cloning and characterization of a putative human axonemal dynein light chain gene.

PMID: 27120127 by Jeanson L., et al. Mutations in GAS8, a gene encoding a nexin-dynein regulatory complex subunit, cause primary ciliary dyskinesia with axonemal disorganization.