PPRC1 Antibodies

AND PPRC1 ELISA kits, PPRC1 Proteins

Many biological assays use antibodies to detect PPRC1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PPRC1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PPRC1 antibodies...

We validate the specificity of these antibodies to PPRC1 by testing them on tissues known to express PPRC1 positively and negatively. Browse below to find the PPRC1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PPRC1 Infographic by Boster Bio

All PPRC1 Products

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Anti-PPRC1 Antibody

4 Q&As

Human, Mouse

ELISA, IHC-P, IF (paraffin)

$335
Cat # A08308-1
100ul

PPRC1 Overview

Facts about Peroxisome proliferator-activated receptor gamma coactivator-related protein 1.

PPRC1 3D structure. Source: alphafold

Peroxisome proliferator-activated receptor gamma coactivator-related protein 1 (PPRC1)

Acts as a coactivator through transcriptional activation of nuclear genes associated with mitochondrial biogenesis and cell growth. Involved in the transcription coactivation of CREB and NRF1 target genes.

Gene Information

Human
Gene Name:	PPRC1
Uniprot:	Q5VV67
Entrez:	23082

Family

Belongs to:

No superfamily

Alternative Names

KIAA0595gamma, coactivator-related 1; peroxisome proliferator-activated receptor gamma, coactivator-related 1; PGC-1 related co-activator; PGC-1-related coactivator

Molecular Weight

Mass (kDA):
177.544 kDA

Genomic Context


Human

Location:	10q24.32
Sequence:	10; NC_000010.11 (102120634..102150333)

Tissue Specificity

Strongly expressed in heart and skeletal muscle, moderately in lung, placenta, intestine, liver, kidney, spleen, thymus, colon and brain. Also expressed in several oncocytic thyroid tumors.

Subcellular Localizations

Nucleus. Colocalizes with NRF1.

Diseases

Immunologic Deficiency Syndromes
Lipodystrophy
Hiv Infections
Mitochondrial Damage

Pathways

Cell Proliferation
Induction Of Apoptosis

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PPRC1

References

PMID: 11340167 by Andersson U., et al. Pgc-1-related coactivator, a novel, serum-inducible coactivator of nuclear respiratory factor 1-dependent transcription in mammalian cells.

PMID: 14550271 by Savagner F., et al. PGC-1-related coactivator and targets are upregulated in thyroid oncocytoma.