PPP2R5A Antibodies

AND PPP2R5A ELISA kits, PPP2R5A Proteins

Many biological assays use antibodies to detect PPP2R5A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PPP2R5A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PPP2R5A antibodies...

We validate the specificity of these antibodies to PPP2R5A by testing them on tissues known to express PPP2R5A positively and negatively. Browse below to find the PPP2R5A antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PPP2R5A Infographic by Boster Bio

All PPP2R5A Products

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Anti-PPP2R5A Antibody

Human, Mouse, Rat

ICC, WB

$405
Cat # A05935
100ul

Anti-PPP2R5A Antibody Picoband®

Human

ELISA, IF, ICC, WB

$370
Cat # A05935-2
100 µg/vial

PPP2R5A Overview

Facts about Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform.

PPP2R5A 3D structure. Source: alphafold

Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform (PPP2R5A)

The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. .

Gene Information

Human
Gene Name:	PPP2R5A
Uniprot:	Q15172
Entrez:	5525

Family

Belongs to:

phosphatase 2A regulatory subunit B56 family

Alternative Names

B56A; MGC131915; PP2A B subunit isoform B56-alpha; PP2A B subunit isoform B'-alpha; PP2A B subunit isoform PR61-alpha; PP2A B subunit isoform R5-alpha; PP2A, B subunit, B' alpha isoform; PP2A, B subunit, B56 alpha isoform; PP2A, B subunit, PR61 alpha isoform; PP2A, B subunit, R5 alpha isoform; PR61A; PR61alpha; protein phosphatase 2, regulatory subunit B (B56), alpha isoform; protein phosphatase 2, regulatory subunit B', alpha isoform; protein phosphatase 2, regulatory subunit B', alpha; serine/threonine protein phosphatase 2A, 56 kDa regulatory subunit, alphaisoform; serine/threonine-protein

Molecular Weight

Mass (kDA):
56.194 kDA

Genomic Context


Human

Location:	1q32.3
Sequence:	1; NC_000001.11 (212285410..212361853)

Tissue Specificity

Widely expressed with the highest expression in heart and skeletal muscle.

Subcellular Localizations

Cytoplasm. Nucleus. Chromosome, centromere. From mitotic prophase to metaphase, localizes at the inner centromere between a pair of sister kinetochores. Decreased expression at the onset of anaphase.

Diseases

Malignant Neoplasms
Neoplasms
Carcinoma
Cell Transformation, Neoplastic
Malnutrition
Lung Neoplasms
Congenital Abnormality
Malignant Neoplasm Of Breast
Cardiomyopathy, Familial Idiopathic
Genomic Instability
Abnormal Cardiac Conduction
Acute Lymphocytic Leukemia
Heart Block

Cardiomyopathy, Dilated
Malignant Neoplasm Of Lung
Carcinogenesis
Conduction Disorder Of The Heart
Cardiomyopathies
Heart Diseases
Leukemia

Interacting Proteins

CHEK2
DZIP1
GNL3
MOS
PPP2CA

PPP2R1A
PPP2R1B
SGO1

Pathways

Dna Repair
Localization
Cell Division
Cell Proliferation
Cell Cycle
Ubiquitin Cycle
Pathogenesis
Cardiac Conduction
Chromosome Segregation

Nuclear Export
Tissue Homeostasis
Regulation Of Phosphorylation

PTMs

Phosphorylation

Dephosphorylation

Research Areas

Wnt Signaling Pathway

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PPP2R5A

References

PMID: 7592815 by McCright B., et al. Identification of a new family of protein phosphatase 2A regulatory subunits.

PMID: 8694763 by Zolnierowicz S., et al. The variable subunit associated with protein phosphatase 2A0 defines a novel multimember family of regulatory subunits.