PPP2R5B Antibodies

AND PPP2R5B ELISA kits, PPP2R5B Proteins

Many biological assays use antibodies to detect PPP2R5B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PPP2R5B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PPP2R5B antibodies...

We validate the specificity of these antibodies to PPP2R5B by testing them on tissues known to express PPP2R5B positively and negatively. Browse below to find the PPP2R5B antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PPP2R5B Infographic by Boster Bio

All PPP2R5B Products

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Product

Figures

Specificity

Applications

Price

Anti-2A5B PPP2R5B Antibody

Human

ELISA, WB

$380
Cat # A09894
100ul

PPP2R5B (NM_006244) Human Recombinant Protein

$813
Cat # PROTQ15173
20 µg

Anti-PPP2R5B Antibody (C-term)

Human

IF, WB

$299
Cat # A09894-1
80 µl

PPP2R5B (NM_006244) Human Over-expression Lysate

Human

$628
Cat # LS005526
100 µg

Anti-PPP2R5B Antibody Picoband®

Human

ELISA, Flow Cytometry, WB

$370
Cat # A09894-2
100 µg/vial

PPP2R5B Overview

Facts about Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform.

PPP2R5B 3D structure. Source: alphafold

Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform (PPP2R5B)

As the regulatory component of the serine/threonine- protein phosphatase 2A (PP2A) holoenzyme, modulates substrate specificity, subcellular localization, and responsiveness to phosphorylation. The phosphorylated form mediates the interaction between PP2A and AKT1, leading to AKT1 dephosphorylation.

Gene Information

Human
Gene Name:	PPP2R5B
Uniprot:	Q15173
Entrez:	5526

Family

Belongs to:

phosphatase 2A regulatory subunit B56 family

Alternative Names

B56B; FLJ35411; PP2A B subunit isoform B56-beta; PP2A B subunit isoform B'-beta; PP2A B subunit isoform PR61-beta; PP2A B subunit isoform R5-beta; PR61B; protein phosphatase 2, regulatory subunit B (B56), beta isoform; protein phosphatase 2, regulatory subunit B', beta isoform; protein phosphatase 2, regulatory subunit B', beta; serine/threonine protein phosphatase 2A, 56 kDa regulatory subunit, betaisoform; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform

Molecular Weight

Mass (kDA):
57.393 kDA

Genomic Context


Human

Location:	11q13.1
Sequence:	11; NC_000011.10 (64917553..64934478)

Tissue Specificity

Highest expression in brain.

Subcellular Localizations

Cytoplasm.

Diseases

Neoplasms
Endocrine Gland Neoplasms
Malignant Neoplasms
Multiple Endocrine Neoplasia Type 1
Multiple Endocrine Neoplasia
Malignant Neoplasm Of Breast
Hereditary Malignant Neoplasm
Pituitary Diseases
Mammary Neoplasms
Malnutrition
Lung Neoplasms
Ataxia

Acute Lymphocytic Leukemia
Malignant Neoplasm Of Lung
Carcinoma
Autistic Disorder
Gastrinoma
Pancreatic Gastrin-producing Neuroendocrinetumor
Leukemia

Interacting Proteins

CHEK2
IER3
PPP2CA
PPP2R1A

Pathways

Lactation
Parturition
Localization

PTMs

Phosphorylation

Cleavage

Dephosphorylation

Research Areas

Wnt Signaling Pathway

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PPP2R5B

References

PMID: 7592815 by McCright B., et al. Identification of a new family of protein phosphatase 2A regulatory subunits.

PMID: 8694763 by Zolnierowicz S., et al. The variable subunit associated with protein phosphatase 2A0 defines a novel multimember family of regulatory subunits.