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- Table of Contents
Facts about Neurabin-2.
Binds across the sides of this F-actin. May play an important role in linking the actin cytoskeleton to the plasma membrane in the synaptic junction.
Rat | |
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Gene Name: | Ppp1r9b |
Uniprot: | O35274 |
Entrez: | 84686 |
Belongs to: |
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No superfamily |
FLJ30345; neurabin II; Neurabin-2; neurabin-II; PPP1R6; PPP1R9; PPP1R9B; Protein phosphatase 1 regulatory subunit 9B; protein phosphatase 1, regulatory (inhibitor) subunit 9B; protein phosphatase 1, regulatory subunit 9B, spinophilin; SPINO; Spinophilin; Spn
Mass (kDA):
89.646 kDA
Rat | |
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Location: | 10q26 |
Sequence: | 10; |
Ubiquitous. Abundantly expressed in the brain. Expressed at highest levels in hippocampus and at lower levels in the cortex, cerebellum and brainstem. Localizes to the dendritic spines of neurons. Also localizes to aspiny neurons, such as GABAergic interneurons.
PMID: 9275233 by Allen P.B., et al. Spinophilin, a novel protein phosphatase 1 binding protein localized to dendritic spines.
PMID: 9452470 by Satoh A., et al. Neurabin-II/spinophilin. An actin filament-binding protein with one pdz domain localized at cadherin-based cell-cell adhesion sites.