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- Table of Contents
Facts about Protein phosphatase 1 regulatory subunit 14A.
Inhibitor of PPP1CA.
Has over 1000-fold higher inhibitory action when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction (By similarity).. .
Mouse | |
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Gene Name: | Ppp1r14a |
Uniprot: | Q91VC7 |
Entrez: | 68458 |
Belongs to: |
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PP1 inhibitor family |
17 kDa PKC-potentiated inhibitory protein of PP1; CPI-1717-kDa PKC-potentiated inhibitory protein of PP1; CPI1717-KDa protein; PKC-potentiated inhibitory protein of PP1; PPP1INL; Protein kinase C-potentiated inhibitor protein of 17 kDa; protein phosphatase 1 regulatory subunit 14A; protein phosphatase 1, regulatory (inhibitor) subunit 14A
Mass (kDA):
16.649 kDA
Mouse | |
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Location: | 7|7 B1 |
Sequence: | 7; |
PMID: 12974676 by Liu Q.-R., et al. GBPI, a novel gastrointestinal- and brain-specific PP1-inhibitory protein, is activated by PKC and inactivated by PKA.