Protein phosphatase 1L Antibodies

AND PPM1L ELISA kits, Protein phosphatase 1L Proteins

Many biological assays use antibodies to detect Protein phosphatase 1L, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Protein phosphatase 1L in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Protein phosphatase 1L antibodies...

We validate the specificity of these antibodies to Protein phosphatase 1L by testing them on tissues known to express PPM1L positively and negatively. Browse below to find the PPM1L antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PPM1L Infographic by Boster Bio

All PPM1L Products

Product

Figures

Specificity

Applications

Price

Anti-PPM1L/Pp2C Epsilon Antibody

Human, Mouse

$360
Cat # A11054
100 µl

Anti-PP2C epsilon PPM1L Antibody

6 Q&As

Human, Mouse, Rat

$399
Cat # A11054-1
100μl

PPM1L (NM_139245) Human Recombinant Protein

$1249
Cat # PROTQ5SGD2
20 µg

PPM1L (NM_139245) Human Over-expression Lysate

Human

$628
Cat # LS151742
100 µg

PPM1L Overview

Facts about Protein phosphatase 1L.

PPM1L 3D structure. Source: alphafold

Protein phosphatase 1L (PPM1L)

Acts as a suppressor of the SAPK signaling pathways by Linking with and dephosphorylating MAP3K7/TAK1 and MAP3K5, and by attenuating the association between MAP3K7/TAK1 and MAP2K4 or MAP2K6.
.

Gene Information

Human
Gene Name:	PPM1L
Uniprot:	Q5SGD2
Entrez:	151742

Family

Belongs to:

PP2C family

Alternative Names

EC 3.1.3; EC 3.1.3.16; MGC132545; MGC132547; PP2C epsilon; PP2CE; PP2CEProtein phosphatase 2C isoform epsilon; PP2C-epsilon; PPM1L; PPM1-LIKE; protein phosphatase 1 (formerly 2C)-like; protein phosphatase 1L; Protein phosphatase 1-like; Protein phosphatase 2C epsilon isoform; protein phosphatase, Mg2+/Mn2+ dependent, 1L

Molecular Weight

Mass (kDA):
41.053 kDA

Genomic Context


Human

Location:	3q25.33-q26.1
Sequence:	3; NC_000003.12 (160755532..161078907)

Tissue Specificity

Ubiquitous. Highly expressed in heart, placenta, lung, liver, kidney and pancreas.

Subcellular Localizations

Membrane; Single-pass type I membrane protein.

Diseases

Metabolic Diseases
Adenomatous Polyposis Coli
Cell Transformation, Neoplastic
Metabolic Syndrome X
Malignant Neoplasms
Obesity
Neoplasms
Colorectal Neoplasms

Polyposis
Polyps
Colorectal Cancer

Pathways

Transport
Ceramide Transport

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PPM1L

References

PMID: 15560375 by Jin F., et al. Molecular cloning and characterization of a novel human protein phosphatase 2C cDNA (PP2C epsilon).

PMID: 17456047 by Saito J., et al. Regulation of apoptosis signal-regulating kinase 1 by protein phosphatase 2Cepsilon.