Liprin-alpha-1 Antibodies

AND PPFIA1 ELISA kits, Liprin-alpha-1 Proteins

Many biological assays use antibodies to detect Liprin-alpha-1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Liprin-alpha-1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Liprin-alpha-1 antibodies...

We validate the specificity of these antibodies to Liprin-alpha-1 by testing them on tissues known to express PPFIA1 positively and negatively. Browse below to find the PPFIA1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PPFIA1 Infographic by Boster Bio

All PPFIA1 Products

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Product

Figures

Specificity

Applications

Price

Anti-Liprin-alpha-1 PPFIA1 Antibody

Human, Mouse

$405
Cat # A05735
100ul

Liprin alpha 1 (PPFIA1) (NM_177423) Human Recombinant Protein

$813
Cat # PROTQ13136
20 µg

Anti-PPFIA1 Antibody Picoband®

Human

ELISA, IF, IHC, ICC, WB

$370
Cat # A05735-1
100 μg/vial

Liprin alpha 1 (PPFIA1) (NM_177423) Human Over-expression Lysate

Human

$960
Cat # LS008500
100 µg

PPFIA1 Overview

Facts about Liprin-alpha-1.

PPFIA1 3D structure. Source: alphafold

Liprin-alpha-1 (PPFIA1)

May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates.

Gene Information

Human
Gene Name:	PPFIA1
Uniprot:	Q13136
Entrez:	8500

Family

Belongs to:

liprin family

Alternative Names

FLJ42630; FLJ43474; LAR-interacting protein 1; LIP.1; LIP-1; LIP1FLJ41337; LIPRIN; Liprin-alpha1; liprin-alpha-1; MGC26800; Protein tyrosine phosphatase receptor type f polypeptide-interacting proteinalpha-1; protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interactingprotein (liprin), alpha 1; PTPRF-interacting protein alpha-1

Molecular Weight

Mass (kDA):
135.779 kDA

Genomic Context


Human

Location:	11q13.3
Sequence:	11; NC_000011.10 (70270687..70384405)

Tissue Specificity

Ubiquitous.

Subcellular Localizations

Cytoplasm. Colocalizes with PTPRF at the ends of focal adhesions most proximal to the cell nucleus.

Diseases

Tissue Adhesions
Neoplasms
Carcinoma
Malignant Squamous Cell Neoplasm
Malignant Neoplasms
Head And Neck Carcinoma
Neoplasm Metastasis
Nervousness
Cell Invasion
Malignant Neoplasm Of Breast
Tumor Angiogenesis
Mammary Neoplasms
Laryngeal Neoplasm

Protrusion
Colonic Neoplasms
Carcinogenesis
Laryngeal Squamous Cell Carcinoma
Metastatic Malignant Neoplasm To The Lymph Node
Glioma
Malignant Tumor Of Colon

Interacting Proteins

CCNH
DTNB
FAM161A
Gria2
Grip1

MBIP
PPP2R5D
TXLNA

Pathways

Localization
Cell Motility
Axon Guidance
Rna Interference
Cell Adhesion
Cell Migration
Mammary Gland Development
Cell Proliferation
Gland Development
Dendrite Development
Synaptic Transmission
Angiogenesis
Pathogenesis

Transport
Synapse Maturation
Regulation Of Dendrite Development
Programmed Cell Death
Immune Response
Cell Cycle
Regulation Of Synapse Assembly

PTMs

Phosphorylation

Acetylation

Dephosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PPFIA1

References

PMID: 7796809 by Serra-Pages C., et al. The LAR transmembrane protein tyrosine phosphatase and a coiled-coil LAR-interacting protein co-localize at focal adhesions.

PMID: 8524829 by Pulido R., et al. The LAR/PTP delta/PTP sigma subfamily of transmembrane protein- tyrosine-phosphatases: multiple human LAR, PTP delta, and PTP sigma isoforms are expressed in a tissue-specific manner and associate with the LAR-interacting protein LIP.1.