POU6F2 Antibodies

AND POU6F2 ELISA kits, POU6F2 Proteins

Many biological assays use antibodies to detect POU6F2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with POU6F2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop POU6F2 antibodies...

We validate the specificity of these antibodies to POU6F2 by testing them on tissues known to express POU6F2 positively and negatively. Browse below to find the POU6F2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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POU6F2 Infographic by Boster Bio

All POU6F2 Products

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Product

Figures

Specificity

Applications

Price

POU6F2 (NM_007252) Human Recombinant Protein

$813
Cat # PROTP78424
20 µg

Anti-POU6F2 Antibody (N-term)

Human

$299
Cat # A10673
80 µl

POU6F2 (NM_007252) Human Over-expression Lysate

Human

$960
Cat # LS011281
100 µg

POU6F2 Overview

Facts about POU domain, class 6, transcription factor 2.

POU6F2 3D structure. Source: alphafold

POU domain, class 6, transcription factor 2 (POU6F2)

Probable transcription factor likely to be involved in early steps in the differentiation of amacrine and ganglion cells. Recognizes and binds to the DNA sequence 5'-ATGCAAAT-3'.

Isoform 1 does not bind DNA. .

Gene Information

Human
Gene Name:	POU6F2
Uniprot:	P78424
Entrez:	11281

Family

Belongs to:

POU transcription factor family

Alternative Names

POU class 6 homeobox 2; Retina-derived POU domain factor 1; retina-derived POU-domain factor-1; RPF1; RPF-1; RPF-1class 6, transcription factor 2; Wilms tumor suppressor locus; WT5; WTSL

Molecular Weight

Mass (kDA):
73.265 kDA

Genomic Context


Human

Location:	7p14.1
Sequence:	7; NC_000007.14 (38977909..39468601)

Tissue Specificity

Expressed only within the CNS, where its expression is restricted to the medical habenulla, to a dispersed population of neurons in the dorsal hypothalamus, and to subsets of ganglion and amacrine cells in the retina.

Subcellular Localizations

Nucleus.

Diseases

Neoplasms
Nephroblastoma
Malignant Neoplasms
Adenocarcinoma
Neoplasm Metastasis
Single Tumor
Lung Neoplasms
Congenital Abnormality
Metastatic Malignant Neoplasm To The Lung
Breast Adenocarcinoma

Kidney Neoplasm
Autistic Disorder
Animal Mammary Neoplasms
Diseases In Twins
Autism Spectrum Disorders

Interacting Proteins

EIF3F
FHL2

Pathways

Cell Cycle
Kidney Development

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/POU6F2

References

PMID: 8601806 by Zhou H., et al. Retina-derived POU-domain factor-1: a complex POU-domain gene implicated in the development of retinal ganglion and amacrine cells.

PMID: 11284034 by Perotti D., et al. Refinement within single yeast artificial chromosome clones of a minimal region commonly deleted on the short arm of chromosome 7 in Wilms tumours.