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- Table of Contents
Facts about Serum paraoxonase/arylesterase 2.
Is not associated with high density lipoprotein. Prevents LDL lipid peroxidation, reverses the oxidation of mildly oxidized LDL, and inhibits the ability of MM-LDL to induce monocyte chemotaxis.
Human | |
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Gene Name: | PON2 |
Uniprot: | Q15165 |
Entrez: | 5445 |
Belongs to: |
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paraoxonase family |
A-esterase 2; Aromatic esterase 2; EC 3.1.1.2; EC 3.1.1.81; paraoxonase 2; paraoxonase nirs; PON 2; PON2; Serum Aryldialkylphosphatase 2; serum paraoxonase/arylesterase 2
Mass (kDA):
39.381 kDA
Human | |
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Location: | 7q21.3 |
Sequence: | 7; NC_000007.14 (95404862..95435072, complement) |
Widely expressed with highest expression in liver, lung, placenta, testis and heart.
Membrane; Peripheral membrane protein.
PMID: 8661009 by Primo-Parmo S.L., et al. The human serum paraoxonase/arylesterase gene (PON1) is one member of a multigene family.
PMID: 9714608 by Mochizuki H., et al. Human PON2 gene at 7q21.3: cloning, multiple mRNA forms, and missense polymorphisms in the coding sequence.