PON2 Antibodies

Serum paraoxonase/arylesterase 2 (PON2)

Capable of hydrolyzing lactones and a number of aromatic carboxylic acid esters. Has antioxidant activity.

Is not associated with high density lipoprotein. Prevents LDL lipid peroxidation, reverses the oxidation of mildly oxidized LDL, and inhibits the ability of MM-LDL to induce monocyte chemotaxis.

Gene Information

Human
Gene Name:	PON2
Uniprot:	Q15165
Entrez:	5445

Family

Belongs to:
paraoxonase family

Alternative Names

A-esterase 2; Aromatic esterase 2; EC 3.1.1.2; EC 3.1.1.81; paraoxonase 2; paraoxonase nirs; PON 2; PON2; Serum Aryldialkylphosphatase 2; serum paraoxonase/arylesterase 2

Molecular Weight

Mass (kDA):
39.381 kDA

Genomic Context

Human
Location:	7q21.3
Sequence:	7; NC_000007.14 (95404862..95435072, complement)

Tissue Specificity

Widely expressed with highest expression in liver, lung, placenta, testis and heart.

Subcellular Localizations

Membrane; Peripheral membrane protein.

Diseases

• Atherosclerosis
• Diabetes Mellitus
• Cardiovascular Diseases
• Coronary Heart Disease
• Diabetes Mellitus, Non-insulin-dependent
• Heart Diseases
• Coronary Artery Disease
• Arteriosclerosis
• Dysequilibrium Syndrome
• Cerebrovascular Accident
• Inflammation
• Cholangiocarcinoma

• Infarction
• Amyotrophic Lateral Sclerosis
• Ischemic Stroke
• Malignant Neoplasms
• Hypertensive Disease
• Alzheimer's Disease
• Kidney Diseases

Pathways

• Pathogenesis
• Quorum Sensing
• Virulence
• Aging
• Localization
• Cholesterol Efflux
• Cell Death
• Secretion
• Transport
• Inflammatory Response
• Lipoprotein Oxidation
• Biofilm Formation
• Glomerular Filtration

• Lipid Oxidation
• Electron Transport
• Electron Transport Chain
• Immune Response
• Glycosylation
• Senescence
• Regulation Of Defense Response

PTMs

• Oxidation
• Phosphorylation
• Methylation

• Glycosylation
• Reduction
• Cleavage

• Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PON2

Best Uses Of The PON2 Marker From Boster Bio

In this article, you'll learn about the many ways to optimize your experiments using the PON2 Marker from Boster Bio. This marker is among the high-affinity secondary antibodies Boster Bio has available. In addition to optimizing your experiments, you'll also discover several optimization tips. Follow these tips to get the most out of your Boster Bio experiments. You'll be astonished at how quickly you see results!

Boster Bio Anti-PON2 Marker

Boster Bio AntiPON2 is an antibody that can be used to perform research. This antibody binds and reacts to human and rat PON2 proteins. This antibody is ideal for a wide range of applications, and you can request a sample now for free! You can also order the Anti-PON2 antibody (C-5) along with the m-IgG2b BP-HRP for your WB or IHC(P) application.

Boster Bio's high-affinity prima antibodies

Boster Bio produces high-quality antibodies for a wide variety of applications, including WB and IHC as well as ELISA. Their antibody collection includes over 12,000 valid antibodies that can be used in ELISA or Western blotting. Each antibody has been optimized to be used in a specific application. The antibodies have been validated against over 29,000 references. Boster Bio provides products for many fields, such as neuroscience and biochemistry. Their quality assurance program guarantees that each product works exactly as they say it will.

These rabbit anti-human PON2 antibodies recognize PON2 protein in human cells and tissues. These antibodies can be used to further study and clinical detection PON2.

High affinity isn't always desirable. High affinity may make it difficult for antibodies to be eluted from the affinity columns. This could lead to the need for harsher methods of purification or denaturing agents. Boster Bio has developed high affinity primary antibodies using the PON2 mark. For more information about this marker, visit the PON2 page on Wikipedia.