PON3 Antibodies

AND PON3 ELISA kits, PON3 Proteins

Many biological assays use antibodies to detect PON3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PON3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PON3 antibodies...

We validate the specificity of these antibodies to PON3 by testing them on tissues known to express PON3 positively and negatively. Browse below to find the PON3 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PON3 Infographic by Boster Bio

All PON3 Products

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Product

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Specificity

Applications

Price

Anti-Serum paraoxonase/lactonase 3 PON3 Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A04029-1
100ul

Anti-PON3 Mouse Monoclonal Antibody [Clone ID: OTI1A5]

Human

IHC, WB

$523
Cat # M04029
100 µl

PON3 (NM_000940) Human Over-expression Lysate

Human

$628
Cat # LS005446
100 µg

PON3 Overview

Facts about Serum paraoxonase/lactonase 3.

PON3 3D structure. Source: alphafold

Serum paraoxonase/lactonase 3 (PON3)

Has low activity to the organophosphate paraxon and aromatic carboxylic acid esters. Rapidly hydrolyzes lactones such as statin prodrugs (e.

g. lovastatin).

Gene Information

Human
Gene Name:	PON3
Uniprot:	Q15166
Entrez:	5446

Family

Belongs to:

paraoxonase family

Alternative Names

EC 3.1.1.2; EC 3.1.1.81; EC 3.1.8.1; paraoxanase-3; paraoxonase 3; PON3; serum paraoxonase/lactonase 3

Molecular Weight

Mass (kDA):
39.607 kDA

Genomic Context


Human

Location:	7q21.3
Sequence:	7; NC_000007.14 (95359872..95396375, complement)

Subcellular Localizations

Secreted, extracellular space.

Diseases

Atherosclerosis
Cardiovascular Diseases
Arteriosclerosis
Coronary Heart Disease
Heart Diseases
Coronary Artery Disease
Diabetes Mellitus
Inflammation
Dysequilibrium Syndrome
Liver Diseases
Amyotrophic Lateral Sclerosis
Inflammatory Response

Obesity
Vascular Diseases
Dental Plaque
Infective Disorder
Alzheimer's Disease
Sclerosis
Primary Lateral Sclerosis

Pathways

Cholesterol Efflux
Pathogenesis
Quorum Sensing
Virulence
Inflammatory Response
Secretion
Aging
Biofilm Formation
Lipid Oxidation
Localization
Senescence
Cell Death
Regulation Of Defense Response

Transport
Acute Inflammatory Response
Regulation Of Defense Response To Virus
Monocyte Chemotaxis
Cellular Senescence
Myeloid Leukocyte Differentiation
Fertilization

PTMs

Oxidation
Phosphorylation

Glycosylation
Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PON3

References

PMID: 8661009 by Primo-Parmo S.L., et al. The human serum paraoxonase/arylesterase gene (PON1) is one member of a multigene family.

PMID: 15772423 by Draganov D.I., et al. Human paraoxonases (PON1, PON2, and PON3) are lactonases with overlapping and distinct substrate specificities.