POMGNT2 Antibodies

AND POMGNT2 ELISA kits, POMGNT2 Proteins

Many biological assays use antibodies to detect POMGNT2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with POMGNT2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop POMGNT2 antibodies...

We validate the specificity of these antibodies to POMGNT2 by testing them on tissues known to express POMGNT2 positively and negatively. Browse below to find the POMGNT2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: Septin9 Next: LINGO1

POMGNT2 Infographic by Boster Bio

All POMGNT2 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-POMGNT2 Antibody

Human, Mouse, Rat

$405
Cat # A11987
100ul

C3orf39 (POMGNT2) (NM_032806) Human Over-expression Lysate

Human

$628
Cat # LS084892
100 µg

Anti-POMGNT2 Antibody Picoband®

Human, Mouse, Rat

ELISA, WB

$370
Cat # A11987-1
100 μg/vial

POMGNT2 Overview

Facts about Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2.

POMGNT2 3D structure. Source: alphafold

Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 (POMGNT2)

O-linked mannose beta-1,4-N- acetylglucosaminyltransferase that transports UDP-N-acetyl-D- glucosamine to the 4-position of the mannose to create N-acetyl- D-glucosamine-beta-1,4-O-D-mannosylprotein. Involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N- acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate- 6-)mannose), a carbohydrate structure present in alpha- dystroglycan (DAG1), which is needed for binding laminin G-like domain-containing extracellular proteins with high affinity.

Gene Information

Human
Gene Name:	POMGNT2
Uniprot:	Q8NAT1
Entrez:	84892

Family

Belongs to:

glycosyltransferase 61 family

Alternative Names

Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2

Molecular Weight

Mass (kDA):
66.615 kDA

Genomic Context


Human

Location:	3p22.1
Sequence:	3; NC_000003.12 (43079229..43106085, complement)

Tissue Specificity

Highly expressed in the brain, muscle, heart, and kidney in both fetus and adult. In the brain, highest expression in the cortex and cerebellum. Highly expressed in the pancreas.

Subcellular Localizations

Endoplasmic reticulum membrane; Single-pass type II membrane protein.

Interacting Proteins

NOTCH2NL

PTMs

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/POMGNT2

References

PMID: 23929950 by Yoshida-Moriguchi T., et al. SGK196 is a glycosylation-specific O-mannose kinase required for dystroglycan function.

PMID: 22958903 by Manzini M.C., et al. Exome sequencing and functional validation in zebrafish identify GTDC2 mutations as a cause of Walker-Warburg syndrome.