PLAAT3 Antibodies

AND PLAAT3 ELISA kits, PLAAT3 Proteins

Many biological assays use antibodies to detect PLAAT3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PLAAT3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PLAAT3 antibodies...

We validate the specificity of these antibodies to PLAAT3 by testing them on tissues known to express PLAAT3 positively and negatively. Browse below to find the PLAAT3 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PLAAT3 Infographic by Boster Bio

All PLAAT3 Products

Product

Figures

Specificity

Applications

Price

HRASLS3 (PLA2G16) (NM_001128203) Human Recombinant Protein

$1249
Cat # PROTP53816
20 µg

Anti-HRASLS3 (PLA2G16) Mouse Monoclonal Antibody [Clone ID: OTI1A5]

Human

IF, IHC, WB

$523
Cat # M34042
100 µl

HRASLS3 (PLA2G16) (NM_007069) Human Over-expression Lysate

Human

$628
Cat # LS011145
100 µg

PLAAT3 Overview

Facts about Phospholipase A and acyltransferase 3.

PLAAT3 3D structure. Source: alphafold

Phospholipase A and acyltransferase 3 (PLAAT3)

Lipid-modifying enzyme that acts as important regulator of adipocyte lipolysis by catalyzing the release of fatty acids from phospholipids in adipose tissue (PubMed:19615464, PubMed:19047760, PubMed:20837014, PubMed:22605381, PubMed:22923616). Shows phospholipase A1 and A2 activity, catalyzing the calcium- independent hydrolysis of acyl groups in various phosphatidylcholines (PC) and phosphatidylethanolamine (PE) (PubMed:19615464, PubMed:19047760, PubMed:20837014, PubMed:22605381, PubMed:22923616).

For many substrates, phospholipase A1 activity is much higher than phospholipase A2 activity (PubMed:19047760). Phospholipase activity causes decreased intracellular levels of ether-type lipids, affecting peroxisome metabolism (By similarity).

Gene Information

Human
Gene Name:	PLAAT3
Uniprot:	P53816
Entrez:	11145

Family

Belongs to:

H-rev107 family

Alternative Names

Phospholipase A and acyltransferase 3

Molecular Weight

Mass (kDA):
17.937 kDA

Genomic Context


Human

Location:	11q12.3-q13.1
Sequence:	11; NC_000011.10 (63574462..63616926, complement)

Tissue Specificity

Widely expressed. low expression, if any, in hematopoietic cells and thymus. In testis, confined to round spermatids. Expressed in normal ovarian epithelial cells. Down- regulated in some ovarian carcinomas and testicular germ cell tumors. Highly expressed in white adipose tissue (PubMed:19136964).

Subcellular Localizations

Cell membrane; Single-pass membrane protein. Cytoplasm. Cytoplasm, perinuclear region. Peroxisome membrane.

Interacting Proteins

PPP2R1A
UBQLN1

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PLAAT3

References

PMID: 9771974 by Husmann K., et al. Transcriptional and translational downregulation of H-REV107, a class II tumour suppressor gene located on human chromosome 11q11-12.

PMID: 11526504 by Siegrist S., et al. hH-Rev107, a class II tumor suppressor gene, is expressed by post- meiotic testicular germ cells and CIS cells but not by human testicular germ cell tumors.