Pituitary homeobox 2 Antibodies

AND PITX2 ELISA kits, Pituitary homeobox 2 Proteins

Many biological assays use antibodies to detect Pituitary homeobox 2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Pituitary homeobox 2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Pituitary homeobox 2 antibodies...

We validate the specificity of these antibodies to Pituitary homeobox 2 by testing them on tissues known to express PITX2 positively and negatively. Browse below to find the PITX2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PITX2 Infographic by Boster Bio

All PITX2 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-PITX2/RGS Antibody Picoband®

1 Q&As

Mouse

Flow Cytometry, WB

$370
Cat # A01636-1
100 μg/vial

Anti-PITX2 Mouse Monoclonal Antibody [Clone ID: OTI1H10]

Human, Mouse, Rat

$523
Cat # M01636
100 µl

PITX2 (NM_153427) Human Over-expression Lysate

Human

$628
Cat # LS005308
100 µg

PITX2 Overview

Facts about Pituitary homeobox 2.

PITX2 3D structure. Source: alphafold

Pituitary homeobox 2 (PITX2)

Controls cell proliferation in a tissue-specific fashion and is involved in morphogenesis. During embryonic development, exerts a part in the growth of muscle progenitors.

May play a role in the proper localization of asymmetric organs such as the heart and gut. Isoform PTX2C is involved in left-right asymmetry the growing embryo (By similarity).

Gene Information

Human
Gene Name:	PITX2
Uniprot:	Q99697
Entrez:	5308

Family

Belongs to:

paired homeobox family

Alternative Names

all1-responsive gene 1; ALL1-responsive protein ARP1; ARP1MGC20144; Brx1; Homeobox protein PITX2; IDG2; IGDS; IGDS2; IHG2; IRID2; Otlx2; paired-like homeodomain 2; Paired-like homeodomain transcription factor 2MGC111022; pituitary homeo box 2; pituitary homeobox 2; PITX2; PTX2; RGS; RGSRIEG1Brx1; rieg bicoid-related homeobox transcription factor 1; RIEG bicoid-related homeobox transcription factor; RIEG; RIEG1; RP1; RS; Solurshin

Molecular Weight

Mass (kDA):
35.37 kDA

Genomic Context


Human

Location:	4q25
Sequence:	4; NC_000004.12 (110617423..110642123, complement)

Subcellular Localizations

Nucleus.

Diseases

Rieger Syndrome
Pituitary Diseases
Eye Abnormalities
Glaucoma
Congenital Abnormality
Malignant Neoplasms
Congenital Heart Defects
Hypoplasia
Irido-corneal Dysgenesis
Neoplasms
Corneal Diseases
Crest Syndrome
Atrial Fibrillation

Malignant Neoplasm Of Breast
Mammary Neoplasms
Cardiac Fibrillation
Tooth Abnormalities
Congenital Absence
Craniofacial Abnormalities
Hydrophthalmos

Interacting Proteins

CTNNB1
FOXC1
Hoxa1
MEF2A
Pou1f1

YBX1

Pathways

Methylation
Cell Proliferation
Heart Looping
Pathogenesis
Dna Methylation
Gastrulation
Eye Development
Localization
Cell Differentiation
Cell Cycle
Heart Development
Organ Morphogenesis
Odontogenesis

Cell Growth
Segmentation
Eye Morphogenesis
Heart Morphogenesis
Neural Tube Closure
Cell Division
Tube Closure

PTMs

Methylation
Phosphorylation
Acetylation

Demethylation
Carboxylation
Dephosphorylation

Research Areas

Stem Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PITX2

References

PMID: 8944018 by Semina E.V., et al. Cloning and characterization of a novel bicoid-related homeobox transcription factor gene, RIEG, involved in Rieger syndrome.

PMID: 9539779 by Arakawa H., et al. Identification and characterization of the ARP1 gene, a target for the human acute leukemia ALL1 gene.