PIK3C3 Antibodies

AND PIK3C3 ELISA kits, PIK3C3 Proteins

Many biological assays use antibodies to detect PIK3C3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PIK3C3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PIK3C3 antibodies...

We validate the specificity of these antibodies to PIK3C3 by testing them on tissues known to express PIK3C3 positively and negatively. Browse below to find the PIK3C3 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PIK3C3 Infographic by Boster Bio

All PIK3C3 Products

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Product

Figures

Specificity

Applications

Price

Anti-PI 3 Kinase Class 3 PIK3C3 Rabbit Monoclonal Antibody

1 Citations 1 Q&As

Human, Mouse, Rat

IHC, WB

$370
Cat # M02356
100 μl

Anti-PIK3C3 Antibody

1 Citations

Human, Mouse, Rat

ELISA, WB

$449
Cat # A02356
0.1 mg

Anti-VPS34 (phospho-Ser249) PIK3C3 Antibody

Human

$482
Cat # A02356S249
100ul

Anti-VPS34 PIK3C3 Antibody

Human, Mouse, Rat

IHC, WB

$405
Cat # A02356-1
100ul

PI 3 Kinase Class 3 (PIK3C3) (NM_002647) Human Over-expression Lysate

Human

$628
Cat # LS005289
100 µg

PIK3C3 Overview

Facts about Phosphatidylinositol 3-kinase catalytic subunit type 3.

PIK3C3 3D structure. Source: alphafold

Phosphatidylinositol 3-kinase catalytic subunit type 3 (PIK3C3)

Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are thought to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2 (PubMed:20643123, PubMed:20208530).

Involved in the transport of lysosomal enzyme precursors to lysosomes. Needed for transport from early to late endosomes (By similarity).

Gene Information

Human
Gene Name:	PIK3C3
Uniprot:	Q8NEB9
Entrez:	5289

Family

Belongs to:

PI3/PI4-kinase family

Alternative Names

EC 2.7.1; EC 2.7.1.137; hVps34; MGC61518; phosphatidylinositol 3-kinase catalytic subunit type 3; Phosphatidylinositol 3-kinase p100 subunit; Phosphoinositide-3-kinase class 3; phosphoinositide-3-kinase, class 3; PI 3-Kinase C3; PI3K type 3; PI3-kinase type 3; PIK3C3; PtdIns-3-kinase type 3; VPS34

Molecular Weight

Mass (kDA):
101.549 kDA

Genomic Context


Human

Location:	18q12.3
Sequence:	18; NC_000018.10 (41955226..42087830)

Tissue Specificity

Ubiquitously expressed, with a highest expression in skeletal muscle.

Subcellular Localizations

Midbody. Late endosome. Cytoplasmic vesicle, autophagosome. As component of the PI3K complex I localized to pre-autophagosome structures. As component of the PI3K complex II localized predominantly to endosomes (Probable). Localizes also to discrete punctae along the ciliary axoneme and to the base of the ciliary axoneme (By similarity).