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PIDD1 Antibodies

AND PIDD1 ELISA kits, PIDD1 Proteins

Many biological assays use antibodies to detect PIDD1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PIDD1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PIDD1 antibodies...

We validate the specificity of these antibodies to PIDD1 by testing them on tissues known to express PIDD1 positively and negatively. Browse below to find the PIDD1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PIDD1 Infographic by Boster Bio

PIDD1 protein infographic

All PIDD1 Products

Product

Figures

Specificity

Applications

Price

Anti-PIDD PIDD1 Antibody (Monoclonal, Anto-1)

1 Q&As

Human, Mouse

IHC-P, WB

$561
Cat # M10708
100μg/vial

Anti-PIDD PIDD1 Antibody

Human, Mouse, Rat

IF, IHC, ICC, WB

$405
Cat # A10708
100ul

LRDD (PIDD1) (NM_145887) Human Over-expression Lysate

Human

$628
Cat # LS055367
100 µg

PIDD1 Overview

Facts about p53-induced death domain-containing protein 1.

PIDD1 3D structure

PIDD1 3D structure. Source: alphafold

p53-induced death domain-containing protein 1 (PIDD1)

Promotes apoptosis downstream of the tumor suppressor as part of the DNA damage/stress response pathway that connects p53/TP53 into apoptosis. Associates with NEMO/IKBKG and RIP1 and enhances sumoylation and ubiquitination of NEMO/IKBKG that's important for activation of the transcription factor NF-kappa-B.

Associates with CASP2/caspase-2 and CRADD/RAIDD, and induces activation of CASP2 that a significant regulator in apoptotic pathways. .

Gene Information

Human
Gene Name:	PIDD1
Uniprot:	Q9HB75
Entrez:	55367

Gene Information

Family

Belongs to:

No superfamily

Family

Alternative Names

p53-induced death domain-containing protein 1

Molecular Weight

Mass (kDA):
99.712 kDA

Molecular Weight

Genomic Context


Human

Location:	11p15.5
Sequence:	11; NC_000011.10 (799179..809867, complement)

Tissue Specificity

Ubiquitous.

Subcellular Localizations

Cytoplasm. Nucleus. Enriched in the nucleus upon DNA damage.

Subcellular Localization

Interacting Proteins

CRADD
MDFI
POGZ

Interacting Proteins

PTMs

Acetylation

Phosphoprotein

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PIDD1

References

PMID: 10825539 by Telliez J.-B., et al. LRDD, a novel leucine rich repeat and death domain containing protein.

PMID: 10973264 by Lin Y., et al. Pidd, a new death-domain-containing protein, is induced by p53 and promotes apoptosis.