PI4KA Antibodies

AND PI4KA ELISA kits, PI4KA Proteins

Many biological assays use antibodies to detect PI4KA, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PI4KA in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PI4KA antibodies...

We validate the specificity of these antibodies to PI4KA by testing them on tissues known to express PI4KA positively and negatively. Browse below to find the PI4KA antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PI4KA Infographic by Boster Bio

All PI4KA Products

Product

Figures

Specificity

Applications

Price

PI4KA (NM_002650) Human Over-expression Lysate

Human

$960
Cat # LS005297
100 µg

PI4KA Overview

Facts about Phosphatidylinositol 4-kinase alpha.

PI4KA 3D structure. Source: alphafold

Phosphatidylinositol 4-kinase alpha (PI4KA)

Acts on phosphatidylinositol (PtdIns) in the first committed step in the creation of the second messenger inositol- 1,4,5,-trisphosphate. .

Gene Information

Human
Gene Name:	PI4KA
Uniprot:	P42356
Entrez:	5297

Family

Belongs to:

PI3/PI4-kinase family

Alternative Names

Phosphatidylinositol 4-kinase alpha

Molecular Weight

Mass (kDA):
236.83 kDA

Genomic Context


Human

Location:	22q11.21
Sequence:	22; NC_000022.11 (20707691..20858812, complement)

Tissue Specificity

Expressed ubiquitously. Highest levels in placenta and brain. Little or no expression in lung, liver, pancreas, testis or leukocytes.

Subcellular Localizations

Cytoplasm. Cell membrane. Localization to the plasma membrane is mediated by the PI4K complex and association with EFR3 (EFR3A or EFR3B), TTC7 (TTC7A or TTC7B) and FAM126 (FAM126A or FAM126B) (PubMed:23229899). Localization to the plasma membrane is regulated by TMEM150A (PubMed:25608530).

Diseases

Polymicrogyria, perisylvian, with cerebellar hypoplasia and arthrogryposis (PMGYCHA)

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PI4KA

References

PMID: 7961848 by Wong K., et al. Cloning and characterization of a human phosphatidylinositol 4- kinase.

PMID: 10101268 by Gehrmann T., et al. Functional expression and characterisation of a new human phosphatidylinositol 4-kinase PI4K230.