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- Table of Contents
Facts about Sesquipedalian-1.
.
Human | |
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Gene Name: | PHETA1 |
Uniprot: | Q8N4B1 |
Entrez: | 144717 |
Belongs to: |
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sesquipedalian family |
Sesquipedalian-1
Mass (kDA):
27.215 kDA
Human | |
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Location: | 12q24.12 |
Sequence: | 12; NC_000012.12 (111360651..111369095, complement) |
Early endosome. Recycling endosome. Golgi apparatus, trans-Golgi network. Cytoplasmic vesicle, clathrin-coated vesicle. Interaction with OCRL may be crucial for targeting to endosome and to the trans-Golgi network. Also found on macropinosomes. Not detected in late endosomes, nor in lysosomes.
PMID: 20133602 by Swan L.E., et al. Two closely related endocytic proteins that share a common OCRL- binding motif with APPL1.
PMID: 21233288 by Noakes C.J., et al. The PH domain proteins IPIP27A and B link OCRL1 to receptor recycling in the endocytic pathway.