Pgp Antibodies

Glycerol-3-phosphate phosphatase (Pgp)

Glycerol-3-phosphate phosphatase hydrolyzing glycerol-3- phosphate into glycerol. Thereby, regulates the cellular levels of glycerol-3-phosphate a metabolic intermediate of glucose, lipid and energy metabolism (PubMed:26755581).

Was also shown to have a 2-phosphoglycolate phosphatase activity and a tyrosine-protein phosphatase action. However, their physiological relevance is unclear (PubMed:26755581, PubMed:24338473).

Gene Information

Mouse
Gene Name:	Pgp
Uniprot:	Q8CHP8
Entrez:	67078

Family

Belongs to:
HAD-like hydrolase superfamily

Alternative Names

EC 3.1.3; EC 3.1.3.18; PGP; Phosphoglycolate Phosphatase

Molecular Weight

Mass (kDA):
34.541 kDA

Genomic Context

Mouse
Location:	17|17 A3.3
Sequence:	17;

Tissue Specificity

Ubiquitously expressed with higher expression in testis, heart, skeletal muscle and islet tissue (at protein level).

Diseases

• Malignant Neoplasms
• Neoplasms
• Leukemia
• Carcinoma
• Malignant Neoplasm Of Breast
• Myeloid Leukemia
• Leukemia, Myelocytic, Acute
• Mammary Neoplasms
• Lung Neoplasms
• Malignant Neoplasm Of Lung
• Malignant Paraganglionic Neoplasm
• Nervousness
• Adenocarcinoma

• Inflammation
• Epilepsy
• Malignant Tumor Of Colon
• Ovarian Neoplasm
• Liver Carcinoma
• Acute Lymphocytic Leukemia
• Colonic Neoplasms

Pathways

• Transport
• Drug Resistance
• Drug Transport
• Innervation
• Localization
• Secretion
• Excretion
• Cell Death
• Cell Cycle
• Cell Proliferation
• Cell Growth
• Pathogenesis
• Intestinal Absorption

• Sensitization
• Auxin Transport
• Induction Of Apoptosis
• Reverse Transcription
• Glycosylation
• Translation
• Regeneration

PTMs

• Phosphorylation
• Cleavage
• Glycosylation
• Methylation
• Reduction
• Acetylation
• Phosphorothioation
• Dephosphorylation
• Carboxylation
• Hydroxylation

• Ubiquitination
• Nitration
• Demethylation
• Biotinylation
• Oxidation
• Amidation
• Prenylation
• Iodination
• Deamination
• Carbamylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Pgp

Boster Bio - The Best Uses Of The PGP Marker

Steven Boster is a well-respected name in the field of high-affinity prima antibodies. But have your heard of the PGP Marker, too? It's time to find out! This article will help guide you in making a wise choice about the PGP Marker. Here's why:

Steven Boster

We've all heard that the PGP marker was introduced in early 1990s and that the PGP protocol was the foundation for the development of the Internet. PGP was invented by the German company Gemalto in the early 1990s and has since been adopted by most web browsers. This technology allows for the decoding and signing of a variety file types, including PDFs.

Primary antibodies with high affinity

Boster Bio, a company that develops high-affinity primary antibodies was founded in 1993. The company has become China's largest catalog anti-body company. PicoKine(tm), a proprietary ELISA tool, is used for high-sensitivity, specificity ELISA Kits. Boster antibodies are therefore approved for use in IHC/WB, ELISA/Flow Cytometry and ELISA applications.

Flow Cytometry is a technique that analyzes cells and other samples. Boster stocks monoclonal and multiclonal antibodies suitable for flow cytometry. These antibodies are highly-cited and have a long shelf life. They are also suitable for immunoprecipitation. The company also offers PCR solutions. The high-affinity antibody can be used for immunoprecipitation.

Boster Bio's high affinity rabbit monoclonal mAbs have the best affinity and specificity. Its PCD platform produces antibodies that can be used in Diagnostics & Therapeutics. The company's proprietary plasma cells discovery technology screens individual cells using proprietary chemistry. This prevents B cells releasing antibodies and keeps them on cell membranes. The antibodies are then released into plasma cells and spleenocytes.

The immune system's second response is an important stage. During the immune system's response to a foreign agent, high-affinity antibody are produced. This phase is when memory B cells are formed. They express IgG and IgA on the surfaces of B cells that have responded to the antigen. Memory B cells have the ability to switch between IgM and mature isotypes, and they also produce IgE antibodies.

The best coating conditions to use for an ELISA plate depend on the test protein or antibody. For some proteins, it is necessary to coat them with more capture protein that they can bind. This will allow for the best detection range. Some proteins need to be coated at a lower concentration than their maximum binding capacity to avoid nonspecific binding. This is called hooking. Proteins trapped in the coating protein prevent them from washing well.

ELISAs can be used to measure specific analytes in crude preparations. These antibodies are highly specific and can remove non-specific binding material. This technology also allows simultaneous use of multiple antibodies. Boster Bio high-affinity prima antibodies ensures more reliable and accurate results. To learn more about our high affinity antibodies, don't be afraid to contact us!

The building blocks of primary antibodies are called complementarity-determining regions. This is a complicated topic. You can read more about the subject on Wikipedia. For example, scientists can make polyclonal primaries antibodies by immunizing host animal with antigens and then extracting the antibodies form the eggs or sera. Once the primary antibody is made, it can be measured and purified.

PGP Marker

Steven Boster was nicknamed "he who converts science in the lavatory" because of the high-affinity primary antibodies he developed for his research. His company grew quickly to become the largest Chinese catalog antibody company in the late 1990s. His company holds hundreds of proprietary trade secrets today, including the PGP Marker. Boster is able to provide the most sensitive and precise ELISA kits.