PGAP3 Antibodies

AND PGAP3 ELISA kits, PGAP3 Proteins

Many biological assays use antibodies to detect PGAP3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PGAP3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PGAP3 antibodies...

We validate the specificity of these antibodies to PGAP3 by testing them on tissues known to express PGAP3 positively and negatively. Browse below to find the PGAP3 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PGAP3 Infographic by Boster Bio

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PGAP3 (NM_033419) Human Over-expression Lysate

Human

$628
Cat # LS093210
100 µg

PGAP3 Overview

Facts about Post-GPI attachment to proteins factor 3.

PGAP3 3D structure. Source: alphafold

Post-GPI attachment to proteins factor 3 (PGAP3)

Involved in the lipid remodeling steps of GPI-anchor maturation. Lipid remodeling steps consist in the creation of 2 saturated fatty chains in the sn-2 position of GPI-anchors proteins.

Required for phospholipase A2 action that removes an acyl-chain in the sn-2 position of GPI-anchors during the remodeling of GPI (Probable). .

Gene Information

Human
Gene Name:	PGAP3
Uniprot:	Q96FM1
Entrez:	93210

Family

Belongs to:

PGAP3 family

Alternative Names

AGLA546; CAB2COS16 homolog; Gene coamplified with ERBB2 protein; MGC9753hCOS16; PER1; per1-like domain containing 1; PERLD1PER1-like domain-containing protein 1; post-GPI attachment to proteins 3; post-GPI attachment to proteins factor 3; PP1498

Molecular Weight

Mass (kDA):
36.475 kDA

Genomic Context


Human

Location:	17q12
Sequence:	17; NC_000017.11 (39671122..39688070, complement)

Tissue Specificity

Ubiquitously expressed, with highest levels in thyroid and placenta.

Subcellular Localizations

Golgi apparatus membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Mainly localizes to Golgi apparatus.

Diseases

Malignant Neoplasms
Stomach Neoplasms
Allergic Asthma
Malignant Neoplasm Of Breast
Reflex, Abnormal
Encephalomyelitis
Polyendocrinopathies, Autoimmune
Experimental Autoimmune Encephalomyelitis
Growth Retardation
Malignant Neoplasm Of Stomach

Autoimmune Reaction
Neoplasms
Asthma
Mammary Neoplasms
Allergy

Pathways

Transport
Cell Development
Immune Response

PTMs

Gpi Anchoring

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PGAP3

References

PMID: 12460457 by Nezu M., et al. Identification of the CAB2/hCOS16 gene required for the repair of DNA double-strand breaks on a core amplified region of the 17q12 locus in breast and gastric cancers.

PMID: 12739007 by Katoh M., et al. MGC9753 gene, located within PPP1R1B-STARD3-ERBB2-GRB7 amplicon on human chromosome 17q12, encodes the seven-transmembrane receptor with extracellular six-cysteine domain.