PELI2 Antibodies

AND PELI2 ELISA kits, PELI2 Proteins

Many biological assays use antibodies to detect PELI2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PELI2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PELI2 antibodies...

We validate the specificity of these antibodies to PELI2 by testing them on tissues known to express PELI2 positively and negatively. Browse below to find the PELI2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PELI2 Infographic by Boster Bio

All PELI2 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Human PELI2 Recombinant Protein

SDS-PAGE

$250
Cat # PROTQ9HAT8
Starting from 10ug

Pellino 2 (PELI2) (NM_021255) Human Over-expression Lysate

Human

$628
Cat # LS057161
100 µg

Anti-PELI2 Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A10176-1
100 µg/vial

PELI2 Overview

Facts about E3 ubiquitin-protein ligase pellino homolog 2.

PELI2 3D structure. Source: alphafold

E3 ubiquitin-protein ligase pellino homolog 2 (PELI2)

E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6.

Mediates IL1B-induced IRAK1 'Lys-63'-linked polyubiquitination and possibly 'Lys-48'-linked ubiquitination. May be important for LPS- and IL1B-induced MAP3K7- dependent, but not MAP3K3-dependent, NF-kappa-B activation.

Gene Information

Human
Gene Name:	PELI2
Uniprot:	Q9HAT8
Entrez:	57161

Family

Belongs to:

pellino family

Alternative Names

pellino (Drosophila) homolog 2; pellino homolog 2 (Drosophila); pellino-2; protein pellino homolog 2

Molecular Weight

Mass (kDA):
46.435 kDA

Genomic Context


Human

Location:	14q22.3
Sequence:	14; NC_000014.9 (56118329..56301586)

Diseases

Innate Immune Response

Interacting Proteins

IRAK1
IRAK4

Pathways

Response To Lipopolysaccharide
Mrna Stabilization
Rna Interference

PTMs

Phosphorylation

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PELI2

References

PMID: 11306823 by Resch K., et al. Assignment of homologous genes, Peli1/PELI1 and Peli2/PELI2, for the Pelle adaptor protein Pellino to mouse chromosomes 11 and 14 and human chromosomes 2p13.3 and 14q21, respectively, by physical and radiation hybrid mapping.

PMID: 12804775 by Jensen L.E., et al. Pellino2 activates the mitogen activated protein kinase pathway.