PDLIM2 Antibodies

AND PDLIM2 ELISA kits, PDLIM2 Proteins

Many biological assays use antibodies to detect PDLIM2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PDLIM2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PDLIM2 antibodies...

We validate the specificity of these antibodies to PDLIM2 by testing them on tissues known to express PDLIM2 positively and negatively. Browse below to find the PDLIM2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PDLIM2 Infographic by Boster Bio

All PDLIM2 Products

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Product

Figures

Specificity

Applications

Price

PDLIM2 (NM_021630) Human Recombinant Protein

$813
Cat # PROTQ96JY6
20 µg

Anti-PDLIM2 Mouse Monoclonal Antibody [Clone ID: OTI11A12]

Human

Flow Cytometry, IF, IHC, WB

$523
Cat # M06506
100 µl

PDLIM2 (NM_176871) Human Over-expression Lysate

Human

$628
Cat # LS064236
100 µg

PDLIM2 Overview

Facts about PDZ and LIM domain protein 2.

PDLIM2 3D structure. Source: alphafold

PDZ and LIM domain protein 2 (PDLIM2)

Probable adapter protein located at the actin cytoskeleton that promotes cell attachment. Necessary for the migratory capacity of epithelial cells.

Overexpression enhances cell adhesion to collagen and fibronectin and inhibits anchorage independent growth. May contribute to tumor cell migratory capacity.

Gene Information

Human
Gene Name:	PDLIM2
Uniprot:	Q96JY6
Entrez:	64236

Family

Belongs to:

No superfamily

Alternative Names

FLJ34715; MYSTIQUE; PDZ and LIM domain 2 (mystique); PDZ and LIM domain protein 2; PDZ-LIM protein mystique; SLIM

Molecular Weight

Mass (kDA):
37.459 kDA

Genomic Context


Human

Location:	8p21.3
Sequence:	8; NC_000008.11 (22578741..22598026)

Subcellular Localizations

Cytoplasm. Nucleus. May be partially nuclear.; [Isoform 1]: Cytoplasm, cytoskeleton. Colocalizes with beta-1 integrin (ITGB1) and alpha-actinin but not with paxillin (PXN).; [Isoform 2]: Cytoplasm, cytoskeleton.; [Isoform 3]: Nucleus.

Diseases

Cell Transformation, Neoplastic
Malignant Neoplasms
Leukemia
Neoplasms
Malignant Paraganglionic Neoplasm
Inflammation
Leukemia, T-cell
Tissue Adhesions
Htlv-i Infections
Autoimmune Reaction
Malignant Neoplasm Of Breast
Metaplastic Cell Transformation
Adult T-cell Lymphoma/leukemia

Neoplasm Metastasis
Inflammatory Bowel Diseases
Neoplasms, Experimental
Membranous Glomerulonephritis
Malignant Tumor Of Colon
Influenza In Birds
Intestinal Diseases

Interacting Proteins

Pathways

Cell Adhesion
Pathogenesis
Methylation
Cell Proliferation
Glomerular Filtration
Cell Differentiation
Oncogenesis
Cell Migration
Osteoblast Differentiation
Cell Development
Dna Methylation
Virulence

Localization
Chemotaxis
T Cell Proliferation
Angiogenesis
Rna Interference
Granuloma Formation

PTMs

Ubiquitination

Methylation

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PDLIM2

References

PMID: 11214971 by Hattori A., et al. Characterization of long cDNA clones from human adult spleen.

PMID: 15659642 by Loughran G., et al. Mystique is a new IGF-I regulated PDZ-LIM domain protein that promotes cell attachment and migration and suppresses anchorage independent growth.