PDIA2 Antibodies

Protein disulfide-isomerase A2 (PDIA2)

Acts as an intracellular estrogen-binding protein. May be involved in regulating cellular levels and biological functions of estrogens in the pancreas.

May act as a chaperone that inhibits aggregation of misfolded proteins. .

Gene Information

Human
Gene Name:	PDIA2
Uniprot:	Q13087
Entrez:	64714

Family

Belongs to:
protein disulfide isomerase family

Alternative Names

Pancreas-specific protein disulfide isomerase; pancreatic protein disulfide isomerase; PDA2; PDI; PDIp; PDIPEC 5.3.4.1; PDIR; protein disulfide isomerase A2; protein disulfide isomerase family A, member 2; protein disulfide isomerase, pancreatic; protein disulfide isomerase-associated 2; protein disulfide-isomerase A2; Rho GDP dissociation inhibitor gamma

Molecular Weight

Mass (kDA):
58.206 kDA

Genomic Context

Human
Location:	16p13.3
Sequence:	16; NC_000016.10 (283164..287215)

Tissue Specificity

Highly expressed in pancreas (at protein level).

Subcellular Localizations

Endoplasmic reticulum lumen.

Diseases

• Autoimmunity
• Diabetes Mellitus, Non-insulin-dependent
• Congenital Heart Defects
• Obesity
• Nervousness
• Thrombosis
• Tissue Adhesions
• Immunologic Tolerance

• Diabetes Mellitus
• Parkinson Disease

Interacting Proteins

• NCK1

Pathways

• Ras Protein Signal Transduction
• Transport
• Cell Adhesion
• Positive Regulation Of Fat Cell Differentiation
• System Development
• Fatty Acid Transport
• Cell Cycle
• Regulation Of Mitosis
• Regulation Of Fat Cell Differentiation
• Cell Differentiation
• Hemostasis
• Lipid Transport
• Visual Perception

• Circadian Rhythm
• Establishment Of Blood-nerve Barrier
• Mitosis
• Glycosylation
• Protein Transport
• Wnt Receptor Signaling Pathway
• Localization

PTMs

• Glycosylation

• Deglycosylation

Research Areas

• Cancer
• Cellular Markers
• ER Markers
• Fibroblast Cell Markers
• Hypoxia

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PDIA2

Boster Bio - Best Uses Of The PDIA2 Marker

You may have wondered about the background of Boster and how he got there. We will be covering Steven Boster's life, including his family and educational background. It will also detail his career. Researchers can now use the PDIA2 marker to pinpoint biological samples' locations. But there is more to this new marker than meets the eye.

History of Steven Boster

Steve Boster, age 77, was taken from us on Sunday, 26 June 2022. Born in Joliet IL, he was a long-standing retail salesman. He was a U.S. Army veteran and was a member Concordia Hall in Staunton. He is also survived by his nieces and nephews.

Steve's family was always his number one priority. He was the person that called first when his car started to break down at 2:05 a.m. and was often the first one to arrive on scene. He was also an avid sports fan. He often drove to work in below-freezing conditions, and often acted as a technician for his friends. Steven Boster is a man of many historical moments. The company that he founded is full with memories.

His educational background

Chris Bushnell is a special advisor to Seattle Mayor Mike McGinn. He once misrepresented his education in business cards and presentations. The special advisor's office has confirmed to PubliCola that he does not have a Ph.D. They also confirmed to PubliCola that Bushnell has never claimed to possess a Ph.D. He holds a Masters in Computer Science from Stanford University. But the truth is somewhere between.