PDE1A Antibodies

AND PDE1A ELISA kits, PDE1A Proteins

Many biological assays use antibodies to detect PDE1A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PDE1A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PDE1A antibodies...

We validate the specificity of these antibodies to PDE1A by testing them on tissues known to express PDE1A positively and negatively. Browse below to find the PDE1A antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PDE1A Infographic by Boster Bio

All PDE1A Products

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Product

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Specificity

Applications

Price

Anti-PDE1A Antibody

Human, Mouse, Rat

$405
Cat # A06723
100ul

Anti-PDE1A Mouse Monoclonal Antibody [Clone ID: OTI7D5]

Human, Mouse, Rat

IHC, WB

$523
Cat # M06723
100 µl

PDE1A (NM_005019) Human Over-expression Lysate

Human

$628
Cat # LS005136
100 µg

PDE1A Overview

Facts about Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A.

PDE1A 3D structure. Source: alphafold

Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (PDE1A)

Cyclic nucleotide phosphodiesterase with a dual- specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a higher affinity for cGMP than for cAMP.

Gene Information

Human
Gene Name:	PDE1A
Uniprot:	P54750
Entrez:	5136

Family

Belongs to:

cyclic nucleotide phosphodiesterase family

Alternative Names

3'-5' cyclic nucleotide phosphodiesterase; 61 kDa Cam-PDE; calcium/calmodulin-dependent 3'-5'-cyclic nucleotide phosphodiesterase 1A; calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase; calmodulin-dependent phosphodiesterase; Cam-PDE 1A; EC 3.1.4; EC 3.1.4.17; HCAM1; hCam-1; HSPDE1A; MGC26303; phosphodiesterase 1A, calmodulin-dependent; phosphodiesterase-1A

Molecular Weight

Mass (kDA):
61.252 kDA

Genomic Context


Human

Location:	2q32.1
Sequence:	2; NC_000002.12 (182136453..182523375, complement)

Tissue Specificity

Several tissues, including brain, kidney, testes and heart.

Diseases

Hypertensive Disease
Depressive Disorder
Major Depressive Disorder
Cardiac Hypertrophy
Hypertrophy
Pulmonary Hypertension
Atherosclerosis
Erectile Dysfunction
Malignant Neoplasms
Heart Diseases
Inflammation
Idiopathic Pulmonary Hypertension

Osteosarcoma
Nervousness
Tissue Adhesions
Autistic Disorder
Vascular Diseases
Right Ventricular Hypertrophy
Melanoma

Pathways

Localization
Cell Proliferation
Transport
Reverse Transcription
Cell Cycle
Acrosome Reaction
Cell Adhesion
Muscle Cell Proliferation
Cell Migration
Cell Cycle Arrest
Translation
Metabolic Process
Prophase

Fibroblast Activation
Lipid Transport
Smooth Muscle Cell Proliferation
Vasodilation
Penile Erection
Cellular Metabolic Process
Sperm Motility

PTMs

Phosphorylation

Biotinylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PDE1A

References

PMID: 8557689 by Loughney K., et al. Isolation and characterization of cDNAs corresponding to two human calcium, calmodulin-regulated, 3',5'-cyclic nucleotide phosphodiesterases.

PMID: 11342109 by Michibata H., et al. Human Ca2+/calmodulin-dependent phosphodiesterase PDE1A: novel splice variants, their specific expression, genomic organization, and chromosomal localization.