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- Table of Contents
Facts about Programmed cell death 1 ligand 2.
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Mouse | |
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Gene Name: | Pdcd1lg2 |
Uniprot: | Q9WUL5 |
Entrez: | 58205 |
Belongs to: |
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immunoglobulin superfamily |
B7-DC; bA574F11.2; Btdc; Butyrophilin B7-DC; Butyrophilin-like Protein; CD273 antigen; CD273; CD273PD-1 ligand 2; MGC142240; PD-1-ligand 2; PDCD1L2MGC142238; PDCD1LG2; PDL2; PD-L2; PDL2B7DC; PD-L2PDCD1 ligand 2; programmed cell death 1 ligand 2; Programmed death ligand 2
Mass (kDA):
27.82 kDA
Mouse | |
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Location: | 19|19 C1 |
Sequence: | 19; |
Expressed in immature and mature bone marrow- derived dendritic cells and splenic dendritic cells. Highly expressed in placenta, liver and weakly expressed in heart, spleen, lymph nodes and thymus. Also expressed in some tumor cell lines of lymphoid origin.
PMID: 11283156 by Tseng S.-Y., et al. B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells.
PMID: 11224527 by Latchman Y., et al. PD-L2 is a second ligand for PD-1 and inhibits T cell activation.