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- Table of Contents
Facts about Zinc finger and BTB domain-containing protein 32.
Probably exerts its repressor effect by preventing GATA3 from binding to DNA. May play a role in regulating the differentiation and activation of helper T-cells (By similarity).
Human | |
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Gene Name: | ZBTB32 |
Uniprot: | Q9Y2Y4 |
Entrez: | 27033 |
Belongs to: |
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krueppel C2H2-type zinc-finger protein family |
Fanconi anemia zinc finger protein; FAXF; FAZFFANCC-interacting protein; Rog; Testis zinc finger protein; TZFPZinc finger protein 538; zinc finger and BTB domain containing 32; zinc finger and BTB domain-containing protein 32; ZNF538FAXFrepressor of GATA
Mass (kDA):
52.963 kDA
Human | |
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Location: | 19q13.12 |
Sequence: | 19; NC_000019.10 (35704481..35717048) |
Predominantly expressed in testis. Some isoforms are ubiquitously expressed.
Nucleus. Located in nuclear speckles.
PMID: 10544010 by Lin W.-C., et al. Identification and gene structure of a novel human PLZF-related transcription factor gene, TZFP.
PMID: 10572087 by Hoatlin M.E., et al. A novel BTB/POZ transcriptional repressor protein interacts with the Fanconi anemia group C protein and PLZF.