PBXIP1 Antibodies

AND PBXIP1 ELISA kits, PBXIP1 Proteins

Many biological assays use antibodies to detect PBXIP1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PBXIP1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PBXIP1 antibodies...

We validate the specificity of these antibodies to PBXIP1 by testing them on tissues known to express PBXIP1 positively and negatively. Browse below to find the PBXIP1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PBXIP1 Infographic by Boster Bio

All PBXIP1 Products

Product

Figures

Specificity

Applications

Price

Anti-PBXIP1 Antibody

Human, Mouse, Rat

IHC, WB

$405
Cat # A07944
100ul

PBXIP1 (NM_020524) Human Over-expression Lysate

Human

$628
Cat # LS057326
100 µg

PBXIP1 Overview

Facts about Pre-B-cell leukemia transcription factor-interacting protein 1.

PBXIP1 3D structure. Source: alphafold

Pre-B-cell leukemia transcription factor-interacting protein 1 (PBXIP1)

Regulator of pre-B-cell leukemia transcription factors (BPXs) function. Inhibits the binding of PBX1-HOX complex to DNA and blocks the transcriptional activity of E2A-PBX1.

Tethers estrogen receptor-alpha (ESR1) to microtubules and enables them to influence estrogen receptors-alpha signaling. .

Gene Information

Human
Gene Name:	PBXIP1
Uniprot:	Q96AQ6
Entrez:	57326

Family

Belongs to:

No superfamily

Alternative Names

Hematopoietic PBX-interacting protein; HPIPpre-B-cell leukemia transcription factor interacting protein 1; pre-B-cell leukemia homeobox interacting protein 1; pre-B-cell leukemia transcription factor-interacting protein 1

Molecular Weight

Mass (kDA):
80.643 kDA

Genomic Context


Human

Location:	1q21.3
Sequence:	1; NC_000001.11 (154944080..154956099, complement)

Tissue Specificity

Expressed in early hematopoietic precursors.

Subcellular Localizations

Cytoplasm, cytoskeleton. Nucleus. Shuttles between the nucleus and the cytosol (PubMed:12360403). Mainly localized in the cytoplasm, associated with microtubules (PubMed:10825160, PubMed:12360403). Detected in small amounts in the nucleus (PubMed:10825160).

Diseases

Cell Transformation, Neoplastic
Leukemia
Mammary Neoplasms
Congenital Heart Defects
Congenital Abnormality
Malignant Neoplasms
Malignant Neoplasm Of Breast

Precursor B-cell Lymphoblastic Leukemia-lymphoma
Growth Arrest

Interacting Proteins

CCNC
DAXX
DEF6
ESR1
MORF4L1

SGTA
WASHC3

Pathways

Cellular Localization
Cell Differentiation
Immune Response
Cell Growth
Interleukin-10 Production
Localization
Nuclear Export

Nuclear Import

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PBXIP1

References

PMID: 10825160 by Abramovich C., et al. Functional cloning and characterization of a novel nonhomeodomain protein that inhibits the binding of PBX1-HOX complexes to DNA.

PMID: 12360403 by Abramovich C., et al. Functional characterization of multiple domains involved in the subcellular localization of the hematopoietic Pbx interacting protein (HPIP).