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- Table of Contents
Facts about Pantothenate kinase 1.
.
Human | |
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Gene Name: | PANK1 |
Uniprot: | Q8TE04 |
Entrez: | 53354 |
Belongs to: |
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type II pantothenate kinase family |
EC 2.7.1.33; hPanK; hPanK1; MGC24596; PANK; PANK1a; PANK1b; pantothenate kinase 1; pantothenate kinase; Pantothenic acid kinase 1
Mass (kDA):
64.339 kDA
Human | |
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Location: | 10q23.31 |
Sequence: | 10; NC_000010.11 (89579495..89645572, complement) |
Isoform 1 is expressed at high levels in brain, heart, kidney, liver, skeletal muscle and testis. Isoform 2 is detected at much lower levels in kidney, liver, brain and testis and is not detected in heart or skeletal muscle.
Cytoplasm.
PMID: 11809413 by Ni X., et al. Cloning and characterization of a novel human pantothenate kinase gene.
PMID: 14523052 by Ramaswamy G., et al. PPARalpha controls the intracellular coenzyme A concentration via regulation of PANK1alpha gene expression.