Shc3 Antibodies

AND Shc3 ELISA kits, Shc3 Proteins

Many biological assays use antibodies to detect Shc3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Shc3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Shc3 antibodies...

We validate the specificity of these antibodies to Shc3 by testing them on tissues known to express Shc3 positively and negatively. Browse below to find the Shc3 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Shc3 Infographic by Boster Bio

All Shc3 Products

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Anti-N-Shc SHC3 Antibody

Human, Mouse, Rat

ELISA, IHC

$380
Cat # A08430
100ul

Shc3 Overview

Facts about SHC-transforming protein 3.

SHC-transforming protein 3 (Shc3)

Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons (By similarity).

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Gene Information

Mouse
Gene Name:	Shc3
Uniprot:	Q61120
Entrez:	20418

Family

Belongs to:

No superfamily

Alternative Names

Neuronal Shc; NSHCDKFZp686H1544; N-Shcsrc homology 2 domain containing transforming protein C3; Protein Rai; RAI; SH2 domain protein C3; SHC (Src homology 2 domain containing) transforming protein 3; SHCCFLJ45325; SHC-transforming protein 3; SHC-transforming protein C; src homology 2 domain-containing transforming protein C3; Src homology 2 domain-containing-transforming protein C3

Molecular Weight

Mass (kDA):
52.121 kDA

Genomic Context


Mouse

Location:	13 A5\|13 26.12 cM
Sequence:	13;

Tissue Specificity

Predominantly expressed in the adult brain.

Diseases

Nervousness
Neuroblastoma
Neoplasms
Malignant Neoplasms
Lymphoma
Anaplastic Lymphoma
Neoplasm Invasiveness
Glioblastoma
Malignant Paraganglionic Neoplasm
Brain Neoplasms
Alzheimer's Disease
Brain Ischemia

Papilloma
Infarction
Tumor Progression
Glioma
Hypoxia
Carcinoma
Tumor Angiogenesis

Pathways

Aging
Regeneration
Rna Interference
Hyperphosphorylation
Cell Migration
Cell Proliferation
Neurogenesis
Localization
Senescence
Membrane Depolarization

Integrin Activation
Cell Growth
Angiogenesis
Pathogenesis
Protein Processing

PTMs

Phosphorylation
Cleavage

Glycosylation
Oxidation

Myristoylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Shc3

References

PMID: 8610109 by O'Bryan J.P., et al. A mammalian adaptor protein with conserved Src homology 2 and phosphotyrosine-binding domains is related to Shc and is specifically expressed in the brain.