PAFAH2 Antibodies

AND PAFAH2 ELISA kits, PAFAH2 Proteins

Many biological assays use antibodies to detect PAFAH2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PAFAH2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PAFAH2 antibodies...

We validate the specificity of these antibodies to PAFAH2 by testing them on tissues known to express PAFAH2 positively and negatively. Browse below to find the PAFAH2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PAFAH2 Infographic by Boster Bio

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PAFAH2 (NM_000437) Human Recombinant Protein

$1249
Cat # PROTQ99487
20 µg

PAFAH2 Overview

Facts about Platelet-activating factor acetylhydrolase 2, cytoplasmic.

PAFAH2 3D structure. Source: alphafold

Platelet-activating factor acetylhydrolase 2, cytoplasmic (PAFAH2)

Has a marked selectivity for phospholipids with short acyl chains at the sn-2 position. May share a common physiologic function with the plasma-type enzyme.

Gene Information

Human
Gene Name:	PAFAH2
Uniprot:	Q99487
Entrez:	5051

Family

Belongs to:

serine esterase family

Alternative Names

EC 3.1.1; EC 3.1.1.47; FLJ26025; HSD-PLA2; platelet-activating factor acetylhydrolase 2 (40kD); platelet-activating factor acetylhydrolase 2, 40kDa; platelet-activating factor acetylhydrolase 2, cytoplasmic; SD-PLA2; Serine-dependent phospholipase A2

Molecular Weight

Mass (kDA):
44.036 kDA

Genomic Context


Human

Location:	1p36.11
Sequence:	1; NC_000001.11 (25959764..25998164, complement)

Tissue Specificity

Broadly expressed in different tissues, but high in B- and T-lymphocytes. In brain, expression is restricted to amygdala and frontal cortex.

Subcellular Localizations

Cytoplasm. Membrane; Lipid-anchor. Endoplasmic reticulum membrane; Lipid-anchor. In resting cells, localizes to intracellular membranes and cytoplasm. Translocates from the cytoplasm to intracellular membranes upon oxidative stress.

Diseases

Injury To Liver
Nerve Degeneration
Inflammation
Mitochondrial Damage
Hydrocephalus

Pathways

Cell Death
Brain Development
Aging

PTMs

Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PAFAH2

References

PMID: 8955149 by Hattori K., et al. cDNA cloning and expression of intracellular platelet-activating factor (PAF) acetylhydrolase II. Its homology with plasma PAF acetylhydrolase.

PMID: 9494101 by Rice S.Q.J., et al. Expression, purification and characterization of a human serine- dependent phospholipase A2 with high specificity for oxidized phospholipids and platelet activating factor.