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- Table of Contents
Facts about Paralemmin-1.
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Human | |
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Gene Name: | PALM |
Uniprot: | O75781 |
Entrez: | 5064 |
Belongs to: |
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paralemmin family |
KIAA0270; paralemmin
Mass (kDA):
42.076 kDA
Human | |
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Location: | 19p13.3 |
Sequence: | 19; NC_000019.10 (708935..748329) |
Widely expressed with highest expression in brain and testis and intermediate expression in heart and adrenal gland.
Cell membrane; Lipid-anchor; Cytoplasmic side. Cell projection, filopodium membrane; Lipid-anchor. Cell projection, axon. Cell projection, dendrite. Cell projection, dendritic spine. Basolateral cell membrane; Lipid-anchor. Apicolateral cell membrane; Lipid-anchor. Translocation to the plasma membrane is enhanced upon stimulation of neuronal activity.
PMID: 9615234 by Burwinkel B., et al. Structure of the human paralemmin gene (PALM), mapping to human chromosome 19p13.3 and mouse chromosome 10, and exclusion of coding mutations in grizzled, mocha, jittery, and hesitant mice.
PMID: 9813098 by Kutzleb C., et al. Paralemmin, a prenyl-palmitoyl-anchored phosphoprotein abundant in neurons and implicated in plasma membrane dynamics and cell process formation.