P2Y purinoceptor 8 Antibodies

AND P2RY8 ELISA kits, P2Y purinoceptor 8 Proteins

Many biological assays use antibodies to detect P2Y purinoceptor 8, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with P2Y purinoceptor 8 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop P2Y purinoceptor 8 antibodies...

We validate the specificity of these antibodies to P2Y purinoceptor 8 by testing them on tissues known to express P2RY8 positively and negatively. Browse below to find the P2RY8 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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P2RY8 Infographic by Boster Bio

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Anti-P2RY8/P2Y8 Antibody

7 Q&As

Human

$399
Cat # A11574
100μl

P2RY8 Overview

Facts about P2Y purinoceptor 8.

P2RY8 3D structure. Source: alphafold

P2Y purinoceptor 8 (P2RY8)

Probable receptor for purines combined to G-proteins. .

Gene Information

Human
Gene Name:	P2RY8
Uniprot:	Q86VZ1
Entrez:	286530

Family

Belongs to:

G-protein coupled receptor 1 family

Alternative Names

G-protein coupled purinergic receptor P2Y8; P2RY8; P2Y purinoceptor 8; P2Y8MGC50878; purinergic receptor P2Y, G-protein coupled, 8

Molecular Weight

Mass (kDA):
40.635 kDA

Genomic Context


Human

Location:	Xp22.33 and Yp11.2
Sequence:	X\|Y; NC_000023.11 (1462576..1537488, complement)

Tissue Specificity

Barely detectable in normal blood leukocytes. Weaker expression was seen in heart, kidney and lung. Not detected in brain.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Leukemia
Acute Lymphocytic Leukemia
Precursor B-cell Lymphoblastic Leukemia-lymphoma
Down Syndrome
Chromosomal Translocation
Chromosome Breakage
Lymphoma
Aneuploidy
Malignant Neoplasms
Splenic Follicular Lymphoma
Neoplasms

Myeloid Leukemia
Nervousness
Cytogenetic Abnormality
Loss Of Chromosome 9p
Hyperdiploidy
Leukemogenesis

Pathways

Pathogenesis
Cell Proliferation
Brain Development
Neurogenesis

PTMs

Glycoprotein

Research Areas

Apoptosis
Cytokine Research
GPCR
Plasma Membrane Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/P2RY8

References

PMID: 11004484 by Adrian K., et al. Expression of purinergic receptors (ionotropic P2X1-7 and metabotropic P2Y1-11) during myeloid differentiation of HL60 cells.

PMID: 15466006 by Cantagrel V., et al. Disruption of a new X linked gene highly expressed in brain in a family with two mentally retarded males.