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Protein orai-3 Antibodies

AND ORAI3 ELISA kits, Protein orai-3 Proteins

Many biological assays use antibodies to detect Protein orai-3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Protein orai-3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Protein orai-3 antibodies...

We validate the specificity of these antibodies to Protein orai-3 by testing them on tissues known to express ORAI3 positively and negatively. Browse below to find the ORAI3 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ORAI3 Infographic by Boster Bio

ORAI3 protein infographic

All ORAI3 Products

Product

Figures

Specificity

Applications

Price

Anti-Protein orai-3 ORAI3 Antibody

Human, Mouse, Rat

ELISA, IHC-P, ICC, WB

$449
Cat # A09399
0.1 mg

Anti-ORAI3 Monoclonal Antibody [2H2G9]

Human, Rat

ELISA, IF, IHC-P, WB

$524
Cat # M09399
0.1 mg

ORAI3 (NM_152288) Human Over-expression Lysate

Human

$628
Cat # LS093129
100 µg

ORAI3 Overview

Facts about Protein orai-3.

ORAI3 3D structure

ORAI3 3D structure. Source: alphafold

Protein orai-3 (ORAI3)

Key regulator or component of store-operated Ca(2+) channel and transcription factor NFAT nuclear import. .

.

Gene Information

Human
Gene Name:	ORAI3
Uniprot:	Q9BRQ5
Entrez:	93129

Gene Information

Family

Belongs to:

Orai family

Family

Alternative Names

ORAI calcium release-activated calcium modulator 3; TMEM142C

Molecular Weight

Mass (kDA):
31.499 kDA

Molecular Weight

Genomic Context


Human

Location:	16p11.2
Sequence:	16; NC_000016.10 (30949068..30954938)

Subcellular Localizations

Membrane; Multi-pass membrane protein.

Subcellular Localization

Diseases

Malignant Neoplasm Of Breast
Immunologic Deficiency Syndromes
Malignant Neoplasms
Inflammation
Autoimmunity
Thrombus
Myopathy
Neoplasms
Mammary Neoplasms
Chimera Disorder
Cardiac Arrhythmia
Leukemia, Myelocytic, Acute
Congenital Myopathy (disorder)

Dysplasia
Vascular System Injuries
Anhydrotic Ectodermal Dysplasias
Multiple Myeloma
Severe Combined Immunodeficiency
Myeloid Leukemia
Trematode Infections

Disease

Interacting Proteins

ORAI1

Interacting Proteins

Pathways

Store-operated Calcium Entry
Secretion
Cell Proliferation
Transport
Cytokine Secretion
Cell Death
Cell Growth
Regulation Of Store-operated Calcium Entry
Vascular Smooth Muscle Contraction
Smooth Muscle Contraction
G1 Phase
Ion Transport
Regulation Of Vascular Smooth Muscle Contraction

Pigmentation
Muscle Contraction
Localization
Cell Division
Drug Resistance
Cytokine Production
Phagocytosis

Pathways

PTMs

Phosphorylation

Glycosylation

Oxidation

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ORAI3

References

PMID: 16582901 by Feske S., et al. A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function.

PMID: 20418871 by Srikanth S., et al. A novel EF-hand protein, CRACR2A, is a cytosolic Ca2+ sensor that stabilizes CRAC channels in T cells.